MAINTAIN - MAintain Functions and INTrinsec capacities with Aging :
Preventive and personalized INterventional Research

Equipe constitutive du CERPOP, UMR 1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
Christelle CANTET •  ITA

2024


2023

  1. Aggarwal G, Morley JE, Vellas B, Nguyen AD, Butler AA; MAPT/DSA Group (Cantet C. collaborator). Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adults. Geroscience. 2023 May 26. doi: 10.1007/s11357-023-00824-3. Epub ahead of print.
  2. Bencivenga L, Strumia M, Rolland Y, Martinez L, Cestac P, Guyonnet S, Andrieu S, Parini A, Lucas A, Vellas B, De Souto Barreto P, Rouch L; MAPT/D. S. A. group (Cantet C. collaborator). Biomarkers of mitochondrial dysfunction and inflammaging in older adults and blood pressure variability. Geroscience. 2023 Apr;45(2):797-809. doi: 10.1007/s11357-022-00697-y.
  3. Giudici KV, de Souto Barreto P, Guyonnet S, Morley JE, Nguyen AD, Aggarwal G, Parini A, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group (Cantet C. collaborator). TNFR-1 and GDF-15 Are Associated With Plasma Neurofilament Light Chain and Progranulin Among Community-Dwelling Older Adults: A Secondary Analysis of the MAPT Study. J Gerontol A Biol Sci Med Sci. 2023 Mar 30;78(4):569-578. doi: 10.1093/gerona/glac244.
  4. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique-Espinoza B, Sourdet S, Rolland Y, Rodríguez-Mañas L, Andrieu S, Vellas B; MAPT/DSA Group (Cantet C. collaborator). Development and Validation of a Cutoff for the Chair Stand Test as a Screening for Mobility Impairment in the Context of the Integrated Care for Older People Program. J Gerontol A Biol Sci Med Sci. 2023 Jan 26;78(1):104-110. doi: 10.1093/gerona/glac055.
  5. Perus L, Mangin JF, Deverdun J, Gutierrez LA, Gourieux E, Fischer C, Van Dokkum LEH, Manesco C, Busto G, Guyonnet S, Vellas B, Gabelle A, Le Bars E; MAPT/DSA group (Cantet C. collaborator). Impact of multidomain preventive strategies on functional brain connectivity in older adults with cognitive complaint: Subset from the Montpellier center of the ancillary MAPT-MRI study. Front Aging Neurosci. 2023 Jan 10;14:971220. doi: 10.3389/fnagi.2022.971220.
  6. Raffin J, Rolland Y, Parini A, Lucas A, Guyonnet S, Vellas B, de Souto Barreto P; MAPT/DSA Group (Cantet C. collaborator). Association between physical activity, growth differentiation factor 15 and bodyweight in older adults: A longitudinal mediation analysis. J Cachexia Sarcopenia Muscle. 2023 Jan 20;14(2):771–80. doi: 10.1002/jcsm.13152. Epub ahead of print.

2022

  1. Fougère B, Goisser S, Cantet C, Soriano G, Guyonnet S, De Souto Barreto P, Cesari M, Andrieu S, Vellas B; MAPT Study Group. Retraction Note to: Omega-3 fatty acid levels in red blood cell membranes and physical decline over 3 years: longitudinal data from the MAPT study.  Geroscience. 2022 Apr;44(2):1173. doi: 10.1007/s11357-021-00505-z.
  2. He L, de Souto Barreto P, Sánchez Sánchez JL, Rolland Y, Guyonnet S, Parini A, Lucas A, Vellas B; MAPT/DSA Group (Cantet C. collaborator). Prospective Associations of Plasma Growth Differentiation Factor 15 With Physical Performance and Cognitive Functions in Older Adults. J Gerontol A Biol Sci Med Sci. 2022 Dec 29;77(12):2420-2428. doi: 10.1093/gerona/glac020.
  3. Giudici KV, Guyonnet S, Cantet C, de Souto Barreto P, Weiner MW, Tosun D, Boschat C, Hudry J, Andrieu S, Vellas B, Schmitt JAJ; Nolan/DSA group. A 1-year randomized controlled trial of a nutritional blend to improve nutritional biomarkers and prevent cognitive decline among community-dwelling older adults: The Nolan Study. Alzheimers Dement (N Y). 2022 Sep 28;8(1):e12314. doi: 10.1002/trc2.12314.
  4. Lu WH, Giudici KV, Morley JE, Guyonnet S, Parini A, Aggarwal G, Nguyen AD, Li Y, Bateman RJ, Vellas B, de Souto Barreto P; MAPT/DSA Group (Cantet C. collaborator). Investigating the combination of plasma amyloid-beta and geroscience biomarkers on the incidence of clinically meaningful cognitive decline in older adults. Geroscience. 2022 Jun;44(3):1489-1503. doi: 10.1007/s11357-022-00554-y.
  5. Molet-Benhamou L, Giudici KV, de Souto Barreto P, Cantet C, Rolland Y; MAPT/DSA group (Andrieu S collaborator). Association between urate-lowering therapies and cognitive decline in community-dwelling older adults. Sci Rep. 2022 Sep 12;12(1):15299. doi: 10.1038/s41598-022-17808-6.
  6. Pagès A, Costa N, Mounié M, Cestac P, De Souto Barreto P, Rolland Y, Vellas B, Molinier L, Juillard-Condat B; MAPT/DSA Group (Cantet C. collaborator). Healthcare Costs Associated with Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm Among Older Patients. Drugs Aging. 2022 May;39(5):367-375. doi: 10.1007/s40266-022-00938-x.
  7. Raffin J, Angioni D, Giudici KV, Valet P, Aggarwal G, Nguyen AD, Morley JE, Guyonnet S, Rolland Y, Vellas B, de Souto Barreto P; MAPT/DSA Group (Cantet C. collaborator). Physical Activity, Body Mass Index, and Blood Progranulin in Older Adults: Cross-Sectional Associations in the MAPT Study. J Gerontol A Biol Sci Med Sci. 2022 Jun 1;77(6):1141-1149. doi: 10.1093/gerona/glac018.
  8. Rouch L, Virecoulon Giudici K, Cantet C, Guyonnet S, Delrieu J, Legrand P, Catheline D, Andrieu S, Weiner M, de Souto Barreto P, Vellas B; Alzheimer's Disease Neuroimaging Initiative. Associations of erythrocyte omega-3 fatty acids with cognition, brain imaging and biomarkers in the Alzheimer's disease neuroimaging initiative: cross-sectional and longitudinal retrospective analyses. Am J Clin Nutr. 2022 Dec 19;116(6):1492-1506. . doi: 10.1093/ajcn/nqac236.
  9. Sanchez-Sanchez JL, Giudici KV, Guyonnet S, Delrieu J, Li Y, Bateman RJ, Parini A, Vellas B, de Souto Barreto P; MAPT/DSA Group (Cantet C. collaborator). Plasma MCP-1 and changes on cognitive function in community-dwelling older adults. Alzheimers Res Ther. 2022 Jan 7;14(1):5. doi: 10.1186/s13195-021-00940-2.
  10. Villars H, Gardette V, Frayssignes P, Deperetti E, Perrin A, Cantet C, Soto-Martin M. Predictors of nursing home placement at 2 years in Alzheimer's disease: A follow-up survey from the THERAD study. Int J Geriatr Psychiatry. 2022 Apr 30;37(6). doi: 10.1002/gps.5724.

2021

  1. De Mauleon A, Delrieu J, Cantet C, Vellas B, Andrieu S, Rosenberg PB, Lyketsos CG, Soto Martin M. Longitudinal Course of Agitation and Aggression in Patients with Alzheimer's Disease in a Cohort Study: Methods, Baseline and Longitudinal Results of the A3C Study. J Prev Alzheimers Dis. 2021;8(2):199-209. doi: 10.14283/jpad.2020.66.
  2. De Mauleon A, Ismail Z, Rosenberg P, Miller D, Cantet C, O'Gorman C, Vellas B, Lyketsos C, Soto M. Agitation in Alzheimer's disease: Novel outcome measures reflecting the International Psychogeriatric Association (IPA) agitation criteria. Alzheimers Dement. 2021 Oct;17(10):1687-1697. doi: 10.1002/alz.12335.
  3. Costa N, Mounié M, Pagès A, Derumeaux H, Rapp T, Guyonnet S, Coley N, Cantet C, Carrié I, Andrieu S, Molinier L. The Cost-Effectiveness of Three Prevention Strategies in Alzheimer's Disease: Results from the Multidomain Alzheimer Preventive Trial (MAPT). J Prev Alzheimers Dis. 2021;8(4):425-435. doi: 10.14283/jpad.2021.47.
  4. He L, Morley JE, Aggarwal G, Nguyen AD, Vellas B, de Souto Barreto P; MAPT/DSA Group (Cantet C. collaborator). Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults. Sci Rep. 2021 Jun 28;11(1):13394. doi: 10.1038/s41598-021-91038-0.
  5. He L, de Souto Barreto P, Giudici KV, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group (Cantet C collaborator). Cross-Sectional and Longitudinal Associations Between Plasma Neurodegenerative Biomarkers and Physical Performance Among Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2021 Sep 13;76(10):1874-1881. doi: 10.1093/gerona/glaa284.
  6. Lu WH, de Souto Barreto P, Rolland Y, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group (Cantet C collaborator). Biological and Neuroimaging Markers as Predictors of 5-Year Incident Frailty in Older Adults: A Secondary Analysis of the MAPT Study. J Gerontol A Biol Sci Med Sci. 2021 Oct 13;76(11):e361-e369. doi: 10.1093/gerona/glaa296.
  7. Raffin J, Rolland Y, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B, Barreto PS; MAPT/DSA Group (Cantet C collaborator). Associations Between Physical Activity, Blood-Based Biomarkers of Neurodegeneration, and Cognition in Healthy Older Adults: The MAPT Study. J Gerontol A Biol Sci Med Sci. 2021 Jul 13;76(8):1382-1390. doi: 10.1093/gerona/glab094.
  8. Rolland Y, Mathieu C, Tavassoli N, Berard E, Laffon de Mazières C, Hermabessière S, Houles M, Perrin A, Krams T, Qassemi S, Cambon A, Magre E, Cantet C, Charpentier S, Lauque D, Azema O, Chicoulaa B, Oustric S, McCambridge C, Gombault-Datzenko E, Molinier L, Costa N, De Souto Barreto P. Factors Associated with Potentially Inappropriate Transfer to the Emergency Department among Nursing Home Residents. J Am Med Dir Assoc. 2021 Dec;22(12):2579-2586.e7. doi: 10.1016/j.jamda.2021.04.002.
  9. Rouch L, De Souto Barreto P, Hanon O, Vidal JS, Amar J, Andrieu S, Cestac P, Rolland Y, Vellas B; MAPT/DSA Group (Cantet C. collaborator). Visit-to-Visit Blood Pressure Variability and Incident Frailty in Older Adults. J Gerontol A Biol Sci Med Sci. 2021 Jul 13;76(8):1369-1375. doi: 10.1093/gerona/glab112.
  10. Takano E, Maltais M, Kondo I, Rolland Y; MAPT/DSA group (Cantet C collaborator). Bidirectional relationship between depressive symptoms and physical performance in community-dwelling older people with subjective memory complaints. Eur Geriatr Med. 2021 Oct;12(5):973-980. doi: 10.1007/s41999-021-00473-9.
  11. Villars H, Cantet C, de Peretti E, Perrin A, Soto-Martin M, Gardette V. Impact of an educational programme on Alzheimer's disease patients' quality of life: results of the randomized controlled trial THERAD. Alzheimers Res Ther. 2021 Sep 12;13(1):152. doi: 10.1186/s13195-021-00896-3.

2020

  1. Delrieu J, Voisin T, Saint-Aubert L, Carrie I, Cantet C, Vellas B, Payoux P, Andrieu S. The impact of a multi-domain intervention on cerebral glucose metabolism: analysis from the randomized ancillary FDG PET MAPT trial. Alzheimers Res Ther. 2020 Oct 19;12(1):134. doi: 10.1186/s13195-020-00683-6.
  2. Giudici KV, de Souto Barreto P, Beard J, Cantet C, Araujo de Carvalho I, Rolland Y, Vellas B; MAPT DSA group. Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study). Maturitas. 2020 Nov;141:39-45. doi: 10.1016/j.maturitas.2020.06.012.
  3. He L, de Souto Barreto P, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group (Cantet C collaborator). Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults. Alzheimers Res Ther. 2020 Oct 8;12(1):128. doi: 10.1186/s13195-020-00697-0.
  4. Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group (Cantet C collaborator). Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 May;68(5):1050-1055. doi: 10.1111/jgs.16343.
  5. Soriano G, De Souto Barreto P, Virecoulon Giudici K, Cantet C, Guyonnet S, Vellas B, Rolland Y, Andrieu S; MAPT DSA Study Group (Cantet C collaborator). Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study. Clin Nutr. 2020 Nov;39(11):3483-3488. doi: 10.1016/j.clnu.2020.03.011.

2019

  1. Coley N, Ngandu T, Lehtisalo J, Soininen H, Vellas B, Richard E, Kivipelto M, Andrieu S; HATICE, FINGER, and MAPT/DSA groups (Cantet C collaborator). Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials. Alzheimers Dement. 2019 Jun;15(6):729-741. doi: 10.1016/j.jalz.2019.03.005.
  2. Delrieu J, Payoux P, Carrié I, Cantet C, Weiner M, Vellas B, Andrieu S. Multidomain intervention and/or omega-3 in nondemented elderly subjects according to amyloid status. Alzheimers Dement. 2019 Nov;15(11):1392-1401. doi: 10.1016/j.jalz.2019.07.008.
  3. Gabelle A, Jaussent I, Bouallègue FB, Lehmann S, Lopez R, Barateau L, Grasselli C, Pesenti C, de Verbizier D, Béziat S, Mariano-Goulart D, Carlander B, Dauvilliers Y; Alzheimer's Disease Neuroimaging Initiative; Multi-Domain Intervention Alzheimer's Prevention Trial study groups (Cantet C collaborator). Reduced brain amyloid burden in elderly patients with narcolepsy type 1. Ann Neurol. 2019 Jan;85(1):74-83. doi: 10.1002/ana.25373.
  4. Girard P, Cantet C, Rolland Y. Reply to Acetaminophen Use and Stroke Risk. J Am Geriatr Soc. 2019 Nov;67(11):2424-2426. doi: 10.1111/jgs.16173.
  5. Girard P, Sourdet S, Cantet C, de Souto Barreto P, Rolland Y. Acetaminophen Safety: Risk of Mortality and Cardiovascular Events in Nursing Home Residents, a Prospective Study. J Am Geriatr Soc. 2019 Jun;67(6):1240-1247. doi:10.1111/jgs.15861.
  6. Lilamand M, Cesari M, Cantet C, Andrieu S. Relationship between brain amyloid deposition and instrumental activities of daily living in older individuals: two analyses from the MAPT study. Geriatr Psychol Neuropsychiatr Vieil. 2019 Jun 1;17(2):211-220. doi: 10.1684/pnv.2019.0801.
  7. Maltais M, de Souto Barreto P, Pothier K, Cantet C, Andrieu S, Rolland Y, Vellas B; MAPT/DSA Study Group. Lifestyle multidomain intervention, omega-3 supplementation, or both for reducing the risk of developing clinically relevant depressive symptoms in older adults with memory complaints? Secondary analysis from the MAPT trial. Exp Gerontol. 2019 Jun;120:28-34. doi: 10.1016/j.exger.2019.02.010.
  8. Rolland Y, Barreto PS, Maltais M, Guyonnet S, Cantet C, Andrieu S, Vellas B. Effect of Long-Term Omega 3 Polyunsaturated Fatty Acid Supplementation with or without Multidomain Lifestyle Intervention on Muscle Strength in Older Adults: Secondary Analysis of the Multidomain Alzheimer Preventive Trial (MAPT). Nutrients. 2019 Aug 16;11(8):1931. doi: 10.3390/nu11081931.
  9. Vermunt L, Sikkes SAM, van den Hout A, Handels R, Bos I, van der Flier WM, Kern S, Ousset PJ, Maruff P, Skoog I, Verhey FRJ, Freund-Levi Y, Tsolaki M, Wallin ÅK, Olde Rikkert M, Soininen H, Spiru L, Zetterberg H, Blennow K, Scheltens P, Muniz-Terrera G, Visser PJ; Alzheimer Disease Neuroimaging Initiative; AIBL Research Group; ICTUS/DSA study (Cantet C collaborator). groups.Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype. Alzheimers Dement. 2019 Jul;15(7):888-898. doi: 10.1016/j.jalz.2019.04.001.