MAINTAIN - MAintain Functions and INTrinsec capacities with Aging :
Preventive and personalized INterventional Research

Equipe constitutive du CERPOP, UMR1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
Yves ROLLAND  •  chercheur


2022

  1. Angioni D, Lu WH, Sourdet S, Macaron T, Takeda C, Guyonnet S, Mangin JF, Rolland Y, de Souto Barreto P, Vellas B. Biomarkers of Age-Related Frailty and Frailty Related to Diseases: An Exploratory, Cross-Sectional Analysis from the MAPT Study. J Nutr Health Aging. 2022;26(6):545-551. doi: 10.1007/s12603-022-1793-9.
     
  2. Angioni D, Cesari M, Raffin J, Virecoulon Giudici K, Mangin JF, Bouyahia A, Chupin M, Fischer C, Gourieux E, Rolland Y, De Breucker S, Vellas B, de Souto Barreto P; MAPT/DSA group. Neuroimaging correlates of persistent fatigue in older adults: A secondary analysis from the Multidomain Alzheimer Preventive Trial (MAPT) trial. Aging Ment Health. 2022 Aug;26(8):1654-1660. doi: 10.1080/13607863.2021.1932737.
     
  3. Beauchet O, Matskiv J, Rolland Y, Schott AM, Allali G. Using Interaction between Cognitive and Motor Impairment for Risk Screening of Major Neurocognitive Disorders: Results of the EPIDOS Observational Cohort Study. Brain Sci. 2022 Jul 31;12(8):1021. doi: 10.3390/brainsci12081021.
     
  4. Beaudart C, Bonnefoy M, Gilbert T, Paillaud E, Raynaud-Simon A, GuÉrin O, Jeandel C, Le Sourd B, Haine M, Ferry M, Rolland Y, Berrut G, Reginster JY, Bruyère O. Quality of life and sarcopenic patients. Geriatr Psychol Neuropsychiatr Vieil. 2022 Feb 7. doi: 10.1684/pnv.2022.1009. Epub ahead of print
     
  5. Bencivenga L, Strumia M, Rolland Y, Martinez L, Cestac P, Guyonnet S, Andrieu S, Parini A, Lucas A, Vellas B, De Souto Barreto P, Rouch L; MAPT/D. S. A. group. Biomarkers of mitochondrial dysfunction and inflammaging in older adults and blood pressure variability. Geroscience. 2022 Dec 1. doi: 10.1007/s11357-022-00697-y. Epub ahead of print.
     
  6. Bencivenga L, De Souto Barreto P, Rolland Y, Hanon O, Vidal JS, Cestac P, Vellas B, Rouch L. Blood pressure variability: A potential marker of aging. Ageing Res Rev. 2022 Sep;80:101677. doi: 10.1016/j.arr.2022.101677.
     
  7. Blain H, Tuaillon E, Gamon L, Pisoni A, Miot S, Delpui V, Si-Mohamed N, Niel C, Rolland Y, Montes B, Groc S, Rafasse S, Dupuy AM, Gros N, Muriaux D, Picot MC, Bousquet J. Receptor binding domain-IgG levels correlate with protection in residents facing SARS-CoV-2 B.1.1.7 outbreaks. Allergy. 2022 Jun;77(6):1885-1894. doi: 10.1111/all.15142.
     
  8. Blain H, Tuaillon E, Gamon L, Pisoni A, Miot S, Rolland Y, Picot MC, Bousquet J. Antibody response after one and two jabs of the BNT162b2 vaccine in nursing home residents: The CONsort-19 study. Allergy. 2022 Jan;77(1):271-281. doi: 10.1111/all.15007.
     
  9. Calcaterra L, Proietti M, Saporiti E, Nunziata V, Rolland Y, Vellas B, Cesari M. Predictors of drug prescription in nursing home residents: results from the INCUR study. Intern Emerg Med. 2022 Jan;17(1):165-171. doi: 10.1007/s11739-021-02841-6.
     
  10. Cesari M, Bernabei R, Vellas B, Fielding RA, Rooks D, Azzolino D, Mariani J, Oliva AA, Bhasin S, Rolland Y. Challenges in the Development of Drugs for Sarcopenia and Frailty - Report from the International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force. J Frailty Aging. 2022;11(2):135-142. doi: 10.14283/jfa.2022.30.
     
  11. Chrusciel J, Letty A, Armaingaud D, Barreto P, Berrut G, Rolland Y, Sanchez S. Factors predictive of adherence to a non-pharmacological intervention in nursing home research: a substudy of the LEDEN trial]. Geriatr Psychol Neuropsychiatr Vieil. 2022 Jun 1;20(2):199-207.  doi: 10.1684/pnv.2022.1037.
     
  12. Da Silva JP, Wargny M, Raffin J, Croyal M, Duparc T, Combes G, Genoux A, Perret B, Vellas B, Guyonnet S, Thalamas C, Langin D, Moro C, Viguerie N, Rolland Y, Barreto PS, Cariou B, Martinez LO; MAPT/DSA Group. Plasma level of ATPase inhibitory factor 1 (IF1) is associated with type 2 diabetes risk in humans: a prospective cohort study. Diabetes Metab. 2022 Sep 26:101391. doi: 10.1016/j.diabet.2022.101391. Epub ahead of print.
     
  13. Damanti S, Ramirez GA, Da Prat V, Bertola A, Manzo E, Vadruccio S, Tresoldi M, Barreto PS, Rolland Y. Selective serotonin reuptake inhibitors and fractures in older nursing home residents: Data from the INCUR study. Maturitas. 2022 Apr;158:37-39. doi: 10.1016/j.maturitas.2021.11.012.
     
  14. de Souto Barreto P, Fabre D, Vellas B, Blain H, Molinier L, Rolland Y. Reduction prevalence of fragility fracture hospitalisation during the COVID-19 lockdown. Arch Osteoporos. 2022 Apr 18;17(1):68. doi: 10.1007/s11657-022-01099-5.
     
  15. de Souto Barreto P, Cesari M, Morley JE, Roberts S, Landi F, Cederholm T, Rolland Y, Vellas B, Fielding R. Appetite Loss and Anorexia of Aging in Clinical Care: An ICFSR Task Force Report. J Frailty Aging. 2022;11(2):129-134. doi: 10.14283/jfa.2022.14.
     
  16. Donini LM, Busetto L, Bischoff SC, Cederholm T, Ballesteros-Pomar MD, Batsis JA, Bauer JM, Boirie Y, Cruz-Jentoft AJ, Dicker D, Frara S, Frühbeck G, Genton L, Gepner Y, Giustina A, Gonzalez MC, Han HS, Heymsfield SB, Higashiguchi T, Laviano A, Lenzi A, Nyulasi I, Parrinello E, Poggiogalle E, Prado CM, Salvador J, Rolland Y, Santini F, Serlie MJ, Shi H, Sieber CC, Siervo M, Vettor R, Villareal DT, Volkert D, Yu J, Zamboni M, Barazzoni R. Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement. Clin Nutr. 2022 Apr;41(4):990-1000. doi: 10.1016/j.clnu.2021.11.014.
     
  17. Donini LM, Busetto L, Bischoff SC, Cederholm T, Ballesteros-Pomar MD, Batsis JA, Bauer JM, Boirie Y, Cruz-Jentoft AJ, Dicker D, Frara S, Frühbeck G, Genton L, Gepner Y, Giustina A, Gonzalez MC, Han HS, Heymsfield SB, Higashiguchi T, Laviano A, Lenzi A, Nyulasi I, Parrinello E, Poggiogalle E, Prado CM, Salvador J, Rolland Y, Santini F, Serlie MJ, Shi H, Sieber CC, Siervo M, Vettor R, Villareal DT, Volkert D, Yu J, Zamboni M, Barazzoni R. Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement. Obes Facts. 2022;15(3):321-335. doi: 10.1159/000521241.
     
  18. Dubucs X, Balen F, Charpentier S, Lauque D, De Souto Barreto P, Tavassoli N, Houze-Cerfon CH, Rolland Y. Factors associated with Emergency Medical Dispatcher request and residents' inappropriate transfers from Nursing Homes to Emergency Department. Eur Geriatr Med. 2022 Apr;13(2):351-357. doi: 10.1007/s41999-021-00574-5.
     
  19. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique-Espinoza B, Rolland Y, Andrieu S, Vellas B; MAPT/DSA group. Clinically meaningful change for the chair stand test: monitoring mobility in integrated care for older people. J Cachexia Sarcopenia Muscle. 2022 Oct;13(5):2331-2339. doi: 10.1002/jcsm.13042.
     
  20. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique Espinoza B, Sourdet S, Rolland Y, Rodriguez-Mañas L, Andrieu S, Vellas B; MAPT/DSA group. Development and validation of a cut-off for the chair stand test as a screening for mobility impairment in the context of the integrated care for older people (ICOPE) program. J Gerontol A Biol Sci Med Sci. 2022 Feb 28:glac055. doi: 10.1093/gerona/glac055. Epub ahead of print.
     
  21. Gonçalves RSDSA, Maciel ÁCC, Rolland Y, Vellas B, de Souto Barreto P. Frailty biomarkers under the perspective of geroscience: A narrative review. Ageing Res Rev. 2022 Nov;81:101737. doi: 10.1016/j.arr.2022.101737.
     
  22. Gautier J, Riou J, Schott AM, Blain H, Rolland Y, Saulnier P, Annweiler C. Higher dietary vitamin D intake is associated with better survival among older women: Results from the French EPIDOS cohort. Front Nutr. 2022 Sep 8;9:974909. doi: 10.3389/fnut.2022.974909.
     
  23. Guion V, De Souto Barreto P, Cesari M, Rolland Y. Quality of Life and Pneumonia in Nursing Home Residents: A 1-Year Observational Study. J Am Med Dir Assoc. 2022 Oct;23(10):1736-1740. doi: 10.1016/j.jamda.2022.06.018.
     
  24. Guion V, Rolland Y. Editorial: Resilience in Nursing Home Residents. J Nutr Health Aging. 2022;26(8):747-748. doi: 10.1007/s12603-022-1832-6.
     
  25. He L, Barreto PS, Sánchez Sánchez JL, Rolland Y, Guyonnet S, Parini A, Lucas A, Vellas B; MAPT/DSA Group. Prospective associations of plasma growth differentiation factor 15 with physical performance and cognitive functions in older adults. J Gerontol A Biol Sci Med Sci. 2022 Jan 17:glac020. doi: 10.1093/gerona/glac020. Epub ahead of print.
     
  26. Lairez O, Blanchard V, Balardy L, Vardon-Bounes F, Cazalbou S, Ruiz S, Collot S, Houard V, Rolland Y, Conil JM, Minville V. COCARDE Study-Cardiac Imaging Phenotype in Patients With COVID-19: Protocol for a Prospective Observational Study. JMIR Res Protoc. 2022 Jan 6;11(1):e24931. doi: 10.2196/24931.
     
  27. Lu WH, Giudici KV, Morley JE, Guyonnet S, Parini A, Aggarwal G, Nguyen AD, Li Y, Bateman RJ, Vellas B, de Souto Barreto P; MAPT/DSA Group (Rolland Y collaborator). Investigating the combination of plasma amyloid-beta and geroscience biomarkers on the incidence of clinically meaningful cognitive decline in older adults. Geroscience. 2022 Jun;44(3):1489-1503. doi: 10.1007/s11357-022-00554-y.
     
  28. Maltais M, de Souto Barreto P, Bowman GL, Smith AD, Cantet C, Andrieu S, Rolland Y. Omega-3 Supplementation for the Prevention of Cognitive Decline in Older Adults: Does It Depend on Homocysteine Levels? J Nutr Health Aging. 2022;26(6):615-620. doi: 10.1007/s12603-022-1809-5.
     
  29. Molet-Benhamou L, Giudici KV, de Souto Barreto P, Cantet C, Rolland Y; MAPT/DSA group. Association between urate-lowering therapies and cognitive decline in community-dwelling older adults. Sci Rep. 2022 Sep 12;12(1):15299. doi: 10.1038/s41598-022-17808-6.
     
  30. Pagès A, Costa N, González-Bautista E, Mounié M, Juillard-Condat B, Molinier L, Cestac P, Rolland Y, Vellas B, De Souto Barreto P; MAPT/DSA Group. Screening for deficits on intrinsic capacity domains and associated healthcare costs. Arch Gerontol Geriatr. 2022 May-Jun;100:104654. doi: 10.1016/j.archger.2022.104654.
     
  31. Pagès A, Costa N, Mounié M, Cestac P, De Souto Barreto P, Rolland Y, Vellas B, Molinier L, Juillard-Condat B; MAPT/DSA Group. Healthcare Costs Associated with Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm Among Older Patients. Drugs Aging. 2022 May;39(5):367-375. doi: 10.1007/s40266-022-00938-x.
     
  32. Pires Da Silva J, Wargny M, Raffin J, Croyal M, Duparc T, Combes G, Genoux A, Perret B, Vellas B, Guyonnet S, Thalamas C, Langin D, Moro C, Viguerie N, Rolland Y, Barreto PS, Cariou B, Martinez LO; MAPT/DSA Group. Plasma level of ATPase inhibitory factor 1 (IF1) is associated with type 2 diabetes risk in humans: A prospective cohort study. Diabetes Metab. 2022 Sep 26;49(1):101391. doi: 10.1016/j.diabet.2022.101391. Epub ahead of print.
     
  33. Raffin J, Angioni D, Giudici KV, Valet P, Aggarwal G, Nguyen AD, Morley JE, Guyonnet S, Rolland Y, Vellas B, Barreto PS; MAPT/DSA Group. Physical activity, body mass index, and blood progranulin in older adults: cross-sectional associations in the MAPT study. J Gerontol A Biol Sci Med Sci. 2022 Jun 1;77(6):1141-1149. doi: 10.1093/gerona/glac018.
     
  34. Rolland Y, Baziard M, De Mauleon A, Dubus E, Saidlitz P, Soto ME. Coronavirus Disease-2019 in Older People with Cognitive Impairment. Clin Geriatr Med. 2022 Aug;38(3):501-517. doi: 10.1016/j.cger.2022.03.002.
     
  35. Rouch L, Rolland Y, Hanon O, Vidal JS, Cestac P, Sallerin B, Andrieu S, Vellas B, Barreto PS; MAPT/DSA Group. Blood pressure, antihypertensive drugs, and incident frailty: The Multidomain Alzheimer Preventive Trial (MAPT). Maturitas. 2022 Aug;162:8-14. doi: 10.1016/j.maturitas.2022.03.001.
     
  36. Sanchez-Sanchez JL, Giudici KV, Guyonnet S, Delrieu J, Li Y, Bateman RJ, Parini A, Vellas B, de Souto Barreto P; MAPT/DSA Group (Rolland Y collaborator). Plasma MCP-1 and changes on cognitive function in community-dwelling older adults. Alzheimers Res Ther. 2022 Jan 7;14(1):5. doi: 10.1186/s13195-021-00940-2.
     
  37. Sanchez-Sanchez JL, He L, Virecoulon Giudici K, Guyonnet S, Parini A, Dray C, Valet P, Pereira O, Vellas B, Rolland Y, de Souto Barreto P. Circulating Levels of Apelin, GDF-15 and Sarcopenia: Lack of Association in the MAPT Study. J Nutr Health Aging. 2022;26(6):564-570. doi: 10.1007/s12603-022-1800-1.
     
  38. Sánchez-Sánchez JL, Rolland Y, Cesari M, de Souto Barreto P. Associations Between Intrinsic Capacity and Adverse Events Among Nursing Home Residents: The INCUR Study. J Am Med Dir Assoc. 2022 May;23(5):872-876.e4. doi: 10.1016/j.jamda.2021.08.035.
     
  39. Silva JAD, Rolland Y, Martinez LO, de Souto Barreto P . Mitochondrial dysfunction and intrinsic capacity: insights from a narrative review. J Gerontol A Biol Sci Med Sci. 2022 Nov 13:glac227. doi: 10.1093/gerona/glac227. Epub ahead of print.

2021

  1. Angioni D, Cesari M, Raffin J, Virecoulon Giudici K, Mangin JF, Bouyahia A, Chupin M, Fischer C, Gourieux E, Rolland Y, De Breucker S, Vellas B, de Souto Barreto P; MAPT/DSA group. Neuroimaging correlates of persistent fatigue in older adults: A secondary analysis from the Multidomain Alzheimer Preventive Trial (MAPT) trial. Aging Ment Health. 2021 Jun 4:1-7. doi: 10.1080/13607863.2021.1932737. Epub ahead of print.
  2. Angioni D, Virecoulon Giudici K, Montoya Martinez M, Rolland Y, Vellas B, de Souto Barreto P. Neuroimaging markers of chronic fatigue in older people: a narrative review. Aging Clin Exp Res. 2021 Jun;33(6):1487-1492. doi : 10.1007/s40520-020-01666-1.
  3. Azzolino D, Marzetti E, Proietti M, Calvani R, de Souto Barreto P, Rolland Y, Cesari M. Lack of energy is associated with malnutrition in nursing home residents: Results from the INCUR study. J Am Geriatr Soc. 2021 Nov;69(11):3242-3248. doi: 10.1111/jgs.17393.
  4. Beaudart C, Bonnefoy M, Gilbert T, Paillaud E, Raynaud-Simon A, Guérin O, Jeandel C, Le Sourd B, Haine M, Ferry M, Rolland Y, Berrut G, Reginster JY, Bruyère O. Quelle qualité de vie pour le patient sarcopénique ? [Which quality of life for the sarcopenic patient?]. Geriatr Psychol Neuropsychiatr Vieil. 2021 Sep 1;19(3):245-252. doi: 10.1684/pnv.2021.0948.
  5. Blain H, Tuaillon E, Gamon L, Pisoni A, Miot S, Delpui V, Si-Mohamed N, Niel C, Rolland Y, Montes B, Groc S, Rafasse S, Dupuy AM, Gros N, Muriaux D, Picot MC, Bousquet J. RBD-IgG levels correlate with protection in residents facing SARS-CoV-2 B.1.1.7 Outbreaks. Allergy. 2021 Oct 15:10.1111/all.15142. doi: 10.1111/all.15142.
  6. Bousquet J, Agache I, Blain H, Jutel M, Ventura MT, Worm M, Del Giacco S, Benetos A, Bilo MB, Czarlewski W, Abdul Latiff AH, Al-Ahmad M, Angier E, Annesi-Maesano I, Atanaskovic-Markovic M, Bachert C, Barbaud A, Bedbrook A, Bennoor KS, Berghea EC, Bindslev-Jensen C, Bonini S, Bosnic-Anticevich S, Brockow K, Brussino L, Camargos P, Canonica GW, Cardona V, Carreiro-Martins P, Carriazo A, Casale T, Caubet JC, Cecchi L, Cherubini A, Christoff G, Chu DK, Cruz AA, Dokic D, El-Gamal Y, Ebisawa M, Eberlein B, Farrell J, Fernandez-Rivas M, Fokkens WJ, Fonseca JA, Gao Y, Gavazzi G, Gawlik R, Gelincik A, Gemicioğlu B, Gotua M, Guérin O, Haahtela T, Hoffmann-Sommergruber K, Hoffmann HJ, Hofmann M, Hrubisko M, lenaIllario M, Irani C, Ispayeva Z, Ivancevich JC, Julge K, Kaidashev I, Khaitov M, Knol E, Kraxner H, Kuna P, Kvedariene V, Lauerma A, Le LT, Le Moing V, Levin M, Louis R, Lourenco O, Mahler V, Martin FC, Matucci A, Milenkovic B, Miot S, Montella E, Morais-Almeida M, Mortz CG, Mullol J, Namazova-Baranova L, Neffen H, Nekam K, Niedoszytko M, Odemyr M, O'Hehir RE, Okamoto Y, Ollert M, Palomares O, Papadopoulos NG, Panzner P, Passalacqua G, Patella V, Petrovic M, Pfaar O, Pham-Thi N, Plavec D, Popov TA, Recto MT, Regateiro FS, Reynes J, Roller-Winsberger RE, Rolland Y, Romano A, Rondon C, Rottem M, Rouadi PW, Salles N, Samolinski B, Santos AF, Serpa FS, Sastre J, Schols JMGA, Scichilone N, Sediva A, Shamji MH, Sheikh A, Skypala I, Smolinska S, Sokolowska M, Sousa-Pinto B, Sova M, Stelmach R, Sturm G, Suppli Ulrik C, Todo-Bom AM, Toppila-Salmi S, Tsiligianni I, Torres M, Untersmayr E, Urrutia Pereira M, Valiulis A, Vitte J, Vultaggio A, Wallace D, Walusiak-Skorupa J, Wang DY, Waserman S, Yorgancioglu A, Yusuf OM, Zernotti M, Zidarn M, Chivato T, Akdis CA, Zuberbier T, Klimek L. Management of anaphylaxis due to COVID-19 vaccines in the elderly. Allergy. 2021 Oct;76(10):2952-2964. doi: 10.1111/all.14838.
  7. Damanti S, de Souto Barreto P, Rolland Y, Astrone P, Cesari M. Malnutrition and physical performance in nursing home residents: results from the INCUR study. Aging Clin Exp Res. 2021 Aug;33(8):2299-2303. doi: 10.1007/s40520-021-01798-y.
  8. De Mauleon A, Lelievre A, Hermabessiere S, Rolland Y. Intervention of companion clowns in a special care unit: a 1-year pilot study. Aging Clin Exp Res. 2021 Dec;33(12):3379-3383. doi: 10.1007/s40520-021-01916-w.
  9. de Souto Barreto P, Maltais M, Rosendahl E, Vellas B, Bourdel-Marchasson I, Lamb SE, Pitkala K, Rolland Y. Exercise Effects on Falls, Fractures, Hospitalizations, and Mortality in Older Adults With Dementia: An Individual-Level Patient Data Meta-analysis. J Gerontol A Biol Sci Med Sci. 2021 Aug 13;76(9):e203-e212. doi: 10.1093/gerona/glaa307.
  10. de Souto Barreto P, Rolland Y. Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined. N Engl J Med. 2021 Aug 5;385(6):572. doi: 10.1056/NEJMc2109509.
  11. de Souto Barreto P, Vellas B, Rolland Y. Physical activity and exercise in the context of SARS-Cov-2: A perspective from geroscience field. Ageing Res Rev. 2021 Mar;66:101258. doi: 10.1016/j.arr.2021.101258.
  12. Frison E, Proust-Lima C, Mangin JF, Habert MO, Bombois S, Ousset PJ, Pasquier F, Hanon O, Paquet C, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Béjot Y, Belin C, Wallon D, Sauvee M, Beaufils E, Bourdel-Marchasson I, Jalenques I, Chupin M, Chêne G, Dufouil C; MEMENTO Cohort Study Group (Rolland Y collaborator). Diabetes Mellitus and Cognition: Pathway Analysis in the MEMENTO Cohort. Neurology. 2021 Aug 24;97(8):e836-e848. doi: 10.1212/WNL.0000000000012440.
  13. González-Bautista E, de Souto Barreto P, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group (members are listed under ‘Contributors’). Screening for intrinsic capacity impairments as markers of increased risk of frailty and disability in the context of integrated care for older people: Secondary analysis of MAPT. Maturitas. 2021 Aug;150:1-6. doi: 10.1016/j.maturitas.2021.05.011.
  14. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique-Espinoza B, Rolland Y, Andrieu S, Vellas B; MAPT/DSA group. Clinically meaningful change for the chair stand test: monitoring mobility in integrated care for older people. J Cachexia Sarcopenia Muscle. 2022 Oct;13(5):2331-2339. doi: 10.1002/jcsm.13042.
  15. Guion V, De Souto Barreto P, Rolland Y. Nursing Home Residents' Functional Trajectories and Mortality After a Transfer to the Emergency Department. J Am Med Dir Assoc. 2021 Feb;22(2):393-398.e3. doi: 10.1016/j.jamda.2020.05.033.
  16. Lafaurie M, Martin-Blondel G, Delobel P, Kamar N, Charpentier S, Sommet A, Moulis G; Covid-Clinic-Toul investigators (Rolland Y collaborator)). Impact of previous exposure to systemic corticosteroids on unfavorable outcome in patients hospitalized for COVID-19. BMC Pharmacol Toxicol. 2021 Mar 11;22(1):14. doi: 10.1186/s40360-021-00480-3.
  17. Lairez O, Blanchard V, Balardy L, Vardon-Bounes F, Cazalbou S, Ruiz S, Collot S, Houard V, Rolland Y, Conil JM, Minville V. Cardiac Imaging Phenotype in Patients with Coronavirus Disease 2019 - COCARDE study: prospective observational study. JMIR Res Protoc. 2021 Aug 6. doi: 10.2196/24931.
  18. Largeaud L, Ribes A, Dubois-Galopin F, Mémier V, Rolland Y, Gaudin C, Rousset D, Geeraerts T, Noel-Savina E, Rieu JB, Vergez F. Major rise of a chronic lymphoid leukemia clone during the course of COVID-19. Int J Lab Hematol. 2021 Apr;43(2):e82-e83. doi: 10.1111/ijlh.13383.
  19. Lu WH, Giudici KV, Rolland Y, Guyonnet S, Mangin JF, Vellas B, de Souto Barreto P. Associations Between Nutritional Deficits and Physical Performance in Community-Dwelling Older Adults. Front Nutr. 2021 Nov 11;8:771470. doi: 10.3389/fnut.2021.771470.
  20. Pagès A, Rouch L, Costa N, Cestac P, De Souto Barreto P, Rolland Y, Vellas B, Molinier L, Juillard-Condat B, Mapt/Dsa Group. Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm among Older Patients: Results from the MAPT Study. Pharmacy (Basel). 2021 Nov 24;9(4):189. doi: 10.3390/pharmacy9040189.
  21. Raffin J, Rolland Y, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B, Barreto PS; MAPT/DSA Group. Associations between physical activity, blood-based biomarkers of neurodegeneration, and cognition in healthy older adults: The MAPT study. J Gerontol A Biol Sci Med Sci. 2021 Jul 13;76(8):1382-1390. doi: 10.1093/gerona/glab094.
  22. Raffin J, Rolland Y, He L, Perus L, Mangin JF, Gabelle A, Virecoulon Giudici K, Vellas B, de Souto Barreto P; MAPT/DSA Group. Cross-sectional and longitudinal interaction effects of physical activity and APOE-ε4 on white matter integrity in older adults: The MAPT study. Maturitas. 2021 Oct;152:10-19. doi: 10.1016/j.maturitas.2021.06.010.
  23. Rolland Y, Mathieu C, Tavassoli N, Berard E, Laffon de Mazières C, Hermabessière S, Houles M, Perrin A, Krams T, Qassemi S, Cambon A, Magre E, Cantet C, Charpentier S, Lauque D, Azema O, Chicoulaa B, Oustric S, McCambridge C, Gombault-Datzenko E, Molinier L, Costa N, De Souto Barreto P. Factors Associated With Potentially Inappropriate Transfer to the Emergency Department Among Nursing Home Residents. J Am Med Dir Assoc. 2021. Dec;22(12):2579-2586.e7. doi: 10.1016/j.jamda.2021.04.002.

2020

  1. Angioni D, Macaron T, Takeda C, Sourdet S, Cesari M, Virecoulon Giudici K, Raffin J, Lu WH, Delrieu J, Touchon J, Rolland Y, de Souto Barreto P, Vellas B. Can We Distinguish Age-Related Frailty from Frailty Related to Diseases ? Data from the MAPT Study. J Nutr Health Aging. 2020;24(10):1144-1151. doi : 10.1007/s12603-020-1518-x.
  2. Aubertin-Leheudre M, Rolland Y. The Importance of Physical Activity to Care for Frail Older Adults During the COVID-19 Pandemic [published online ahead of print, 2020 Apr 30]. J Am Med Dir Assoc. 2020;S1525-8610(20)30353-4. doi:10.1016/j.jamda.2020.04.022.
  3. Beaudart C, Bruyère O, Cruz-Jentoft AJ, Vaquero-Pinto MN, Locquet M, Bauer J, Cooper C, Rolland Y, Dupuy C, Landi F, Reginster JY, Maggi S, Rizzoli R, Hiligsmann M; European Society for Clinical and Economic Aspect of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Patient's Engagement in the Identification of Critical Outcomes in Sarcopenia. J Am Med Dir Assoc. 2020;21(2):284–286. doi:10.1016/j.jamda.2019.09.004.
  4. Blain H, Rolland Y, Schols JMGA, Cherubini A, Miot S, O'Neill D, Martin FC, Guérin O, Gavazzi G, Bousquet J, Petrovic M, Gordon AL, Benetos A. August 2020 Interim EuGMS guidance to prepare European Long-Term Care Facilities for COVID-19. Eur Geriatr Med. 2020 Dec;11(6):899-913. doi: 10.1007/s41999-020-00405-z.
  5. Bousquet J, Czarlewski W, Zuberbier T, Mullol J, Blain H, Cristol JP, De La Torre R, Le Moing V, Pizarro Lozano N, Bedbrook A, Agache I, Akdis CA, Canonica GW, Cruz AA, Fiocchi A, Fonseca JA, Fonseca S, Gemicioğlu B, Haahtela T, Iaccarino G, Ivancevich JC, Jutel M, Klimek L, Kuna P, Larenas-Linnemann DE, Melén E, Okamoto Y, Papadopoulos NG, Pfaar O, Reynes J, Rolland Y, Rouadi PW, Samolinski B, Sheikh A, Toppila-Salmi S, Valiulis A, Choi HJ, Kim HJ, Anto JM. Spices to Control COVID-19 Symptoms: Yes, but Not Only…. Int Arch Allergy Immunol. 2020 Dec 22:1-7. doi: 10.1159/000513538. Epub ahead of print.
  6. Briand M, De Nadaï T, Balardy L, Rolland Y, Nourhashemi F, Sourdet S, Vellas B. Autonomy and dependence in the elderly. Rev Prat. 2020 Mar;70(3):e97-e105. French. PMID: 32877080.
  7. Briand M, De Nadaï T, Balardy L, Rolland Y, Nourhashemi F, Sourdet S, Vellas B.Scales assessing geriatric dependence. Rev Prat. 2020 Mar;70(3):e106-e107. PMID : 32877081.
  8. de Souto Barreto P, Maltais M, Rosendahl E, Vellas B, Bourdel-Marchasson I, Lamb SE, Pitkala K, Rolland Y. Exercise effects on falls, fractures, hospitalizations and mortality in older adults with dementia: an individual-level patient data meta-analysis. J Gerontol A Biol Sci Med Sci. 2020 Dec 7:glaa307. doi : 10.1093/gerona/glaa307. Epub ahead of print.
  9. Donini LM, Busetto L, Bauer JM, Bischoff S, Boirie Y, Cederholm T, Cruz-Jentoft AJ, Dicker D, Frühbeck G, Giustina A, Gonzalez MC, Han HS, Heymsfield SB, Higashiguchi T, Laviano A, Lenzi A, Parrinello E, Poggiogalle E, Prado CM, Rodriguez JS, Rolland Y, Santini F, Siervo M, Tecilazich F, Vettor R, Yu J, Zamboni M, Barazzoni R. Critical appraisal of definitions and diagnostic criteria for sarcopenic obesity based on a systematic review. Clin Nutr. 2020 Aug;39(8):2368-2388. doi: 10.1016/j.clnu.2019.11.024.
  10. El Haddad K, de Souto Barreto P, de Mazieres CL, Rolland Y. Effect of a geriatric intervention aiming to improve polypharmacy in nursing homes [published online ahead of print, 2020 May 27]. Eur Geriatr Med. 2020;10.1007/s41999-019-00279-w. doi:10.1007/s41999-019-00279-w.
  11. El Haddad K, Rolland Y, Gérard S, Mourey L, Sourdet S, Vellas B, Stephan E, Abellan Van Kan G, de Souto Barreto P, Balardy L. No Difference in the Phenotypic Expression of Frailty among Elderly Patients Recently Diagnosed with Cancer Vs Cancer Free Patients. J Nutr Health Aging. 2020;24(2):147–151. doi:10.1007/s12603-019-1293-8.
  12. Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B. Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. J Prev Alzheimers Dis. 2020;7(1):56–64. doi:10.14283/jpad.2019.50.
  13. Guerville F, De Souto Barreto P, Coley N, Andrieu S, Mangin JF, Chupin M, Payoux P, Ousset PJ, Rolland Y, Vellas B; MAPT/DSA group. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration. J Am Geriatr Soc. 2020 Nov 20. doi: 10.1111/jgs.16954.
  14. Giudici KV, de Souto Barreto P, Beard J, Cantet C, Araujo de Carvalho I, Rolland Y, Vellas B; MAPT DSA group. Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study). Maturitas. 2020 Nov;141:39-45. doi: 10.1016/j.maturitas.2020.06.012.
  15. Guion V, De Souto Barreto P, Rolland Y. Nursing Home Residents' Functional Trajectories and Mortality After a Transfer to the Emergency Department. J Am Med Dir Assoc. 2021 Feb;22(2):393-398.e3. doi: 10.1016/j.jamda.2020.05.033.
  16. Hiligsmann M, Beaudart C, Bruyère O, Biver E, Bauer J, Cruz-Jentoft AJ, Gesmundo A, Goisser S, Landi F, Locquet M, Maggi S, Rizzoli R, Rolland Y, Vaquero N, Cooper C, Reginster JY; European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Outcome Priorities for Older Persons With Sarcopenia. J Am Med Dir Assoc. 2020;21(2):267–271.e2. doi:10.1016/j.jamda.2019.08.02.
  17. Lu WH, Giudici KV, Rolland Y, Guyonnet S, Li Y, Bateman RJ, de Souto Barreto P, Vellas B. Prospective Associations between Plasma Amyloid-Beta 42/40 and Frailty in Community-Dwelling Older Adults. J Prev Alzheimers Dis. 2021;8(1):41-47. doi: 10.14283/jpad.2020.60.
  18. Lu WH, de Souto Barreto P, Rolland Y, Rodríguez-Mañas L, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Cross-sectional and prospective associations between cerebral cortical thickness and frailty in older adults. Exp Gerontol. 2020 Oct 1;139:111018. doi: 10.1016/j.exger.2020.111018.
  19. Lu WH, Barreto PS, Rolland Y, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Biological and Neuroimaging Markers as Predictors of 5-year Incident Frailty in Older Adults: a Secondary Analysis of the MAPT study. J Gerontol A Biol Sci Med Sci. 2020 Nov 27:glaa296. doi: 10.1093/gerona/glaa296. Epub ahead of print.
  20. Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group. Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020;68(5):1050-1055. doi:10.1111/jgs.16343.
  21. Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B. Re: Prospective Associations between Diffusion Tensor Imaging Parameters and Frailty in Older Adults [published online ahead of print, 2020 Apr 16]. J Am Geriatr Soc. 2020;10.1111/jgs.16456. doi:10.1111/jgs.16456
  22. Maltais M, Rolland Y, Boisvert-Vigneault K, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Vellas B, de Souto Barreto P. Prospective associations between physical activity levels and white matter integrity in older adults: results from the MAPT study. Maturitas. 2020;137:24-2 doi:10.1016/j.maturitas.2020.04.012.
  23. Maquet J, Lafaurie M, Sommet A, Moulis G; Covid-Clinic-Toul investigators group, Alvarez M, Amar J, Attal M, Balardy L, Balen F, Beyne-Rauzy O, Bouali O, Bounes F, Bureau C, Buscail L, Calviere L, Charpentier S, Chollet F, Claudet I, Constantin A, Debard A, Delavigne K, Delobel P, Delrieu J, Didier A, Faruch M, Fourcade O, Georges B, Grunenwald E, Guyonnet S, Hanaire H, Hein C, Kamar N, Lairez O, Mansat P, Martin-Blondel G, Minville V, Pariente J, Paul C, Payoux P, Pugnet G, Piel-Julian ML, Recher C, Rolland Y, Ruyssen-Witrand A, Sabatier J, Sailler L, Salles JP, Sans N, Secher M, Sevely A, Silva S, Thalamas C, Toulza O. Thrombocytopenia is independently associated with poor outcome in patients hospitalized for COVID-19. Br J Haematol. 2020 Sep;190(5):e276-e279. doi: 10.1111/bjh.16950.
  24. Martin-Blondel G, Ruiz S, Murris M, Faguer S, Duhalde V, Eyvrard F, Izopet J, Mansuy JM, Rolland Y, Delavigne K, Guimbaud R, Pugnet G, Conil JM, Georges B, Delobel P, Minville V, Silva Sifontes S, Concordet D, Gandia P. Hydroxychloroquine in Coronavirus Disease 2019 Patients: What Still Needs to Be Known About the Kinetics. Clin Infect Dis. 2020 Dec 31;71(11):2962-2964. doi: 10.1093/cid/ciaa558.
  25. Masciocchi E, Maltais M, El Haddad K, Virecoulon Giudici K, Rolland Y, Vellas B, de Souto Barreto P. Defining Vitality Using Physical and Mental Well-Being Measures in Nursing Homes: A Prospective Study. J Nutr Health Aging. 2020;24(1):37–42. doi:10.1007/s12603-019-1285-8.
  26. Nunziata V, Proietti M, Saporiti E, Calcaterra L, Rolland Y, Vellas B, Cesari M. Pain Management in Nursing Home Residents: Results from the INCUR Study. J Nutr Health Aging. 2020;24(9):1019-1022. doi: 10.1007/s12603-020-1443-z.
  27. Pamoukdjian F, Laurent M, Martinez-Tapia C, Rolland Y, Paillaud E, Canoui-Poitrine F. Frailty Parameters, Morbidity and Mortality in Older Adults with Cancer: A Structural Equation Modelling Approach Based on the Fried Phenotype. J Clin Med. 2020;9(6):1826. doi:10.3390/jcm9061826.
  28. Parrotta I, Maltais M, Rolland Y, Spampinato DA, Robert P, de Souto Barreto P, Vellas B; MAPT/DSA group. The association between apathy and frailty in older adults: a new investigation using data from the Mapt study. Aging Ment Health. 2020 Dec;24(12):1985-1989. doi: 10.1080/13607863.2019.1650890.
  29. Rodriguez-Mañas L, Araujo de Carvalho I, Bhasin S, Bischoff-Ferrari HA, Cesari M, Evans W, Hare JM, Pahor M, Parini A, Rolland Y, Fielding RA, Walston J, Vellas B. ICFSR Task Force Perspective on Biomarkers for Sarcopenia and Frailty. J Frailty Aging. 2020. 9(1):4–8. doi: 10.14283/jfa.2019.32.
  30. Rolland Y, Cesari M, Morley JE, Merchant R, Vellas B. Editorial: COVID19 Vaccination in Frail People. Lots of Hope and Some Questions. J Nutr Health Aging. 2021;25(2):146-147. doi: 10.1007/s12603-021-1591-9.
  31. Rolland Y, Tavassoli N, de Souto Barreto P, Perrin A, Laffon de Mazières C, Rapp T, Hermabessière S, Tournay E, Vellas B, Andrieu S. Systematic Dementia Screening by Multidisciplinary Team Meetings in Nursing Homes for Reducing Emergency Department Transfers: The IDEM Cluster Randomized Clinical Trial. JAMA Netw Open. 2020;3(2):e200049. doi:10.1001/jamanetworkopen.2020.0049.
  32. Ruiz JG, Dent E, Morley JE, Merchant RA, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer JM, Cesari M, Chen LK, Cruz-Jentoft AJ, De Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster JY, Rodriguez-Mañas L, Rolland Y, Sanford AM, Sinclair AJ, Viña J, Waters DL, Won Won C, Woo J, Vellas B. Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. J Nutr Health Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3.
  33. Sánchez-Rodríguez D, Rolland Y, Annweiler C. Malnutrition according to the European Society of Clinical Nutrition and Metabolism (ESPEN) definition and falls in general older population: Findings in the EPIDOS study-Toulouse cohort. Clin Nutr. 2020;39(1):318–319. doi:10.1016/j.clnu.2019.11.013.
  34. Soriano G, De Souto Barreto P, Virecoulon Giudici K, Cantet C, Guyonnet S, Vellas B, Rolland Y, Andrieu S; MAPT DSA Study Group. Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study. Clin Nutr. 2020;S0261-5614(20)30114-X. doi:10.1016/j.clnu.2020.03.011.
  35. Troesch B, Eggersdorfer M, Laviano A, Rolland Y, Smith AD, Warnke I, Weimann A, Calder PC. Expert Opinion on Benefits of Long-Chain Omega-3 Fatty Acids (DHA and EPA) in Aging and Clinical Nutrition. Nutrients. 2020 Aug 24;12(9):2555. doi: 10.3390/nu12092555.
Publications 2019