MAINTAIN - MAintain Functions and INTrinsec capacities with Aging :
Preventive and personalized INterventional Research

Equipe constitutive du CERPOP, UMR 1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
Virginie GARDETTE chercheure


  1. Couret A, Lapeyre-Mestre M, Gombault-Datzenko E, Renoux A, Villars H, Gardette V. Healthcare use patterns before Alzheimer's disease and related diseases identification and future healthcare trajectory. Int J Geriatr Psychiatry. 2023 Jan;38(1):e5849. doi: 10.1002/gps.5849.
  2. Escourrou E, Joyeux T, Guilhem M, Oustric S, Gardette V. How general practitioners perceive the aging trajectory of oldest-old - A qualitative study. BMC Prim Care. 2023 Jan 9;24(1):5. doi: 10.1186/s12875-023-01964-3.


  1. Clarke L, Castor-Newton MJ, Angénieux O, Lapeyre-Mestre M, Gardette V. La population âgée en Guyane : état des lieux et enjeux pour le système de santé [The elderly in French Guiana: health status and challenges for the Guianese health system]. Sante Publique. 2022;34(5):695-707. French. doi: 10.3917/spub.225.0695.
  2. Elyn A, Gardette V, Renoux A, Sourdet S, Nourhashemi F, Sanou B, Dutech M, Muller P, Gallini A. Potential determinants of unfavourable healthcare utilisation trajectories during the last year of life of people with incident Alzheimer Disease or Related Syndromes: a nationwide cohort study using administrative data. Age Ageing. 2022 Mar 1;51(3):afac053. doi: 10.1093/ageing/afac053.
  3. Escourrou E, Laurent S, Leroux J, Oustric S, Gardette V. The shift from old age to very old age: an analysis of the perception of aging among older people. BMC Prim Care. 2022 Jan 11;23(1):3. doi: 10.1186/s12875-021-01616-4.
  4. Villars H, Gardette V, Frayssignes P, Deperetti E, Perrin A, Cantet C, Soto-Martin M. Predictors of nursing home placement at 2 years in Alzheimer's disease: A follow-up survey from the THERAD study. Int J Geriatr Psychiatry. 2022 Apr 30;37(6):10.1002/gps.5724. doi: 10.1002/gps.5724. Epub ahead of print.


  1. Charnay M, Gardette V, Raynaud JP, Parant O, Franchitto L. Réunions pluridisciplinaires en maternité pour les femmes à haut risque médico-psycho-social: étude qualitative entre 2012-2018 [Preventive staff meetings in maternity ward for women at high medico-psycho-social risk: qualitative study between 2012 and 2018]. Gynecol Obstet Fertil Senol. 2021 Nov;49(11):830-837. . doi: 10.1016/j.gofs.2021.03.006.
  2. Coley N, Coniasse-Brioude D, Igier V, Fournier T, Poulain JP, Andrieu S; ACCEPT study group (Gardette V collaborator).. Disparities in the participation and adherence of older adults in lifestyle-based multidomain dementia prevention and the motivational role of perceived disease risk and intervention benefits: an observational ancillary study to a randomised controlled trial. Alzheimers Res Ther. 2021 Sep 24;13(1):157. doi: 10.1186/s13195-021-00904-6.
  3. Gallini A, Jegou D, Lapeyre-Mestre M, Couret A, Bourrel R, Ousset PJ, Fabre D, Andrieu S, Gardette V. Development and Validation of a Model to Identify Alzheimer's Disease and Related Syndromes in Administrative Data. Curr Alzheimer Res. 2021;18(2):142-156. doi: 10.2174/1567205018666210416094639.
  4. Gallini A, Renoux A, Siep S, Roustan A, Voisin T, Escudier G, Muller P, Gardette V. Clustering 5-Year Multidimensional Health Care Trajectory Patterns in Alzheimer's Disease and Related Syndromes. J Am Med Dir Assoc. 2021 Mar 6:S1525-8610(21)00198-5. doi: 10.1016/j.jamda.2021.01.085. Epub ahead of print.
  5. Esclassan R, Valera MC, Bergia JM, Canceill T, Mendes LC, Bailleul-Forestier I, Gardette V, Vaysse F, Gurgel-Georgelin M, Noirrit E. Morbidity and Mortality Review in a University Dental Hospital: A Necessary Tool to Improve Quality of Care. Eur J Dent. 2021 May;15(2):307-311. doi: 10.1055/s-0040-1719233.
  6. Villars H, Cantet C, de Peretti E, Perrin A, Soto-Martin M, Gardette V. Impact of an educational programme on Alzheimer's disease patients' quality of life: results of the randomized controlled trial THERAD. Alzheimers Res Ther. 2021 Sep 12;13(1):152. doi: 10.1186/s13195-021-00896-3.


  1. Chauliac N, Leaune E, Gardette V, Poulet E, Duclos A. Suicide Prevention Interventions for Older People in Nursing Homes and Long-Term Care Facilities: A Systematic Review. J Geriatr Psychiatry Neurol. 2020 Nov;33(6):307-315. doi: 10.1177/0891988719892343.
  2. Couret A, Gallini A, Poncet M, Renoux A, Lapeyre-Mestre M, Gardette V. Benzodiazepine Dispensing to Persons With Dementia in France, 2011-2016: A Nationwide Study. J Am Med Dir Assoc. 2020;21(6):830-836. doi:10.1016/j.jamda.2020.02.019.
  3. Escourrou E, Durrieu F, Chicoulaa B, Dupouy J, Oustric S, Andrieu S, Gardette V. Cognitive, functional, physical, and nutritional status of the oldest old encountered in primary care: a systematic review. BMC Fam Pract. 2020;21(1):58. Published 2020 Mar 27. doi: 10.1186/s12875-020-01128-7.
  4. Gombault-Datzenko E, Gallini A, Carcaillon-Bentata L, Fabre D, Nourhashemi F, Andrieu S, Rachas A, Gardette V. Alzheimer's disease and related syndromes and hospitalization: a nationwide 5-year longitudinal study. Eur J Neurol. 2020 Aug;27(8):1436-1447. doi: 10.1111/ene.14256.
  5. Poncet M, Gardette V, Couret A, Renoux A, Lapeyre-Mestre M, Gallini A. Benzodiazepine exposure in subjects with incident Alzheimer's disease and related syndromes in France: a longitudinal study 2011-2017. Int Clin Psychopharmacol. 2020 Sep;35(5):270-278. doi: 10.1097/YIC.0000000000000312.


  1. André L, Gallini A, Montastruc F, Coley N, Montastruc JL, Vellas B, Andrieu S, Gardette V; MAPT/DSA study group. Anticholinergic exposure and cognitive decline in older adults: effect of anticholinergic exposure definitions in a 3-year analysis of the multidomain Alzheimer preventive trial (MAPT) study.  Br J Clin Pharmacol. 2019 Jan;85(1):71-99.  doi: 10.1111/bcp.13734.
  2. Chauliac N, Leaune E, Gardette V, Poulet E, Duclos A. Suicide Prevention Interventions for Older People in Nursing Homes and Long-Term Care Facilities: A Systematic Review [published online ahead of print, 2019 Dec 16]. J Geriatr Psychiatry Neurol. 2019;891988719892343. doi:10.1177/0891988719892343.
  3. Andre L, Gallini A, Montastruc F, Montastruc JL, Piau A, Lapeyre-Mestre M, Gardette V. Association between anticholinergic (atropinic) drug exposure and cognitive function in longitudinal studies among individuals over 50 years old: a systematic review. Eur J Clin Pharmacol. 2019;75(12):1631-1644 doi:10.1007/s00228-019-02744-8.