MAINTAIN - MAintain Functions and INTrinsec capacities with Aging :
Preventive and personalized INterventional Research

Equipe constitutive du CERPOP, UMR 1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
Sandrine ANDRIEU •  chercheure
 

2020

  1. Akenine U, Barbera M, Beishuizen CR, Fallah Pour M, Guillemont J, Rosenberg A, Coley N, Mangialasche F, Salo L, Savy S, Pols AJ, Andrieu S, Richard E, Soininen H, Moll van Charante E, Kivipelto M; HATICE study group. Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context. BMJ Open. 2020 Aug 6;10(8):e037050. doi: 10.1136/bmjopen-2020-037050.
  2. Cavedo E, Lista S, Khachaturian Z, Amouyel P, Herholz K, Jack Jr CR, Sperling R, Cummings J, Blennow K, O'Bryant S, Frisoni GB, Khachaturian A, Kivipelto M, Klunk W, Broich K, Andrieu S, Thiebaut de Schotten M, Mangin JF, Lammertsma AA, Johnson K, Teipel S, Drzezga A, Bokde A, Colliot O, Bakardjian H, Zetterberg H, Dubois B, Vellas B, Schneider LS, Hampel H. The Road Ahead to Cure Alzheimer's Disease: Development of Biological Markers and Neuroimaging Methods for Prevention Trials Across all Stages and Target Populations. J Prev Alzheimers Dis. 2014;1(3):181–20 doi: 10.14283/jpad.2014.32.
  3. Coley N, Hoevenaar-Blom MP, van Dalen JW, Moll van Charante EP, Kivipelto M, Soininen H, Andrieu S, Richard E; PRODEMOS consortium, the preDIVA study group, the MAPT/DSA group, and the HATICE consortium. Dementia risk scores as surrogate outcomes for lifestyle-based multidomain prevention trials-rationale, preliminary evidence and challenges. Alzheimers Dement. 2020 Dec;16(12):1674-1685.. doi:10.1002/alz.12169.
  4. Delrieu J, Voisin T, Saint-Aubert L, Carrie I, Cantet C, Vellas B, Payoux P, Andrieu S. The impact of a multi-domain intervention on cerebral glucose metabolism: analysis from the randomized ancillary FDG PET MAPT trial. Alzheimers Res Ther. 2020 Oct 19;12(1):134. doi: 10.1186/s13195-020-00683-6.
  5. Escourrou E, Durrieu F, Chicoulaa B, Dupouy J, Oustric S, Andrieu S, Gardette V. Cognitive, functional, physical, and nutritional status of the oldest old encountered in primary care: a systematic review. BMC Fam Pract. 2020 Mar 27;21(1):58. doi: 10.1186/s12875-020-01128-7.
  6. Gombault-Datzenko E, Gallini A, Carcaillon-Bentata L, Fabre D, Nourhashemi F, Andrieu S, Rachas A, Gardette V. Alzheimer's disease and related syndromes and hospitalization: a nationwide 5-year longitudinal study. Eur J Neurol. 2020 Aug;27(8):1436-1447. doi:10.1111/ene.14256.
  7. Gonzalez-Bautista E, Andrieu S, Gutiérrez-Robledo LM, García-Chanes RE, de Souto Barreto P. In the quest of a Standard Index of Intrinsic Capacity. A Critical Literature Review. J Nutr Health Aging. 2020;24(9):959-965. doi: 10.1007/s12603-020-1394-4.
  8. Guerville F, De Souto Barreto P, Coley N, Andrieu S, Mangin JF, Chupin M, Payoux P, Ousset PJ, Rolland Y, Vellas B; MAPT/DSA group. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration. J Am Geriatr Soc. 2020 Nov 20. doi: 10.1111/jgs.16954.
  9. He L, de Souto Barreto P, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group (Andrieu S collaborator). Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults. Alzheimers Res Ther. 2020 Oct 8;12(1):128. doi:10.1186/s13195-020-00697-0.
  10. Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, Carrillo MC, Bain LJ. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimers Dement. 2011;7(2):127–132. doi:10.1016/j.jalz.2011.02.005.
  11. Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I, Caramelli P, Chen C, Chertkow H, Chew E, Choi SH, Chowdhary N, Crivelli L, Torre R, Du Y, Dua T, Espeland M, Feldman HH, Hartmanis M, Hartmann T, Heffernan M, Henry CJ, Hong CH, Håkansson K, Iwatsubo T, Jeong JH, Jimenez-Maggiora G, Koo EH, Launer LJ, Lehtisalo J, Lopera F, Martínez-Lage P, Martins R, Middleton L, Molinuevo JL, Montero-Odasso M, Moon SY, Morales-Pérez K, Nitrini R, Nygaard HB, Park YK, Peltonen M, Qiu C, Quiroz YT, Raman R, Rao N, Ravindranath V, Rosenberg A, Sakurai T, Salinas RM, Scheltens P, Sevlever G, Soininen H, Sosa AL, Suemoto CK, Tainta-Cuezva M, Velilla L, Wang Y, Whitmer R, Xu X, Bain LJ, Solomon A, Ngandu T, Carrillo MC. World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. Alzheimers Dement. 2020 Jul;16(7):1078-1094. doi: 10.1002/alz.12123.
  12. Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I, Caramelli P, Chen C, Chertkow H, Chew E, Choi SH, Chowdhary N, Crivelli L, Torre R, Du Y, Dua T, Espeland M, Feldman HH, Hartmanis M, Hartmann T, Heffernan M, Henry CJ, Hong CH, Håkansson K, Iwatsubo T, Jeong JH, Jimenez-Maggiora G, Koo EH, Launer LJ, Lehtisalo J, Lopera F, Martínez-Lage P, Martins R, Middleton L, Molinuevo JL, Montero-Odasso M, Moon SY, Morales-Pérez K, Nitrini R, Nygaard HB, Park YK, Peltonen M, Qiu C, Quiroz YT, Raman R, Rao N, Ravindranath V, Rosenberg A, Sakurai T, Salinas RM, Scheltens P, Sevlever G, Soininen H, Sosa AL, Suemoto CK, Tainta-Cuezva M, Velilla L, Wang Y, Whitmer R, Xu X, Bain LJ, Solomon A, Ngandu T, Carrillo MC. World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia [published online ahead of print, 2020 Jul 5]. Alzheimers Dement. 2020;10.1002/alz.12123. doi: 10.1002/alz.12123.
  13. Maltais M, de Souto Barreto P, Perus L, et al. Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group (Andrieu S collaborator).  Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults [published online ahead of print, 2020 Jan 25]. J Am Geriatr Soc. 2020;10.1111/jgs.16343. doi: 10.1111/jgs.16343.
  14. Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B, Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group (Andrieu S collaborator). Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020;68(5):1050-1055. doi: 10.1111/jgs.16343.
  15. Rolland Y, Tavassoli N, de Souto Barreto P, Perrin  A, Laffon de Mazières C, Rapp T, Hermabessière S, Tournay E, Vellas B, Andrieu S. Systematic Dementia Screening by Multidisciplinary Team Meetings in Nursing Homes for Reducing Emergency Department Transfers: The IDEM Cluster Randomized Clinical Trial. JAMA Netw Open. 2020 Feb 5;3(2):e200049. doi: 10.1001/jamanetworkopen.2020.0049.
  16. Rosenberg A, Coley N, Soulier A, Kulmala J, Soininen H, Andrieu S, Kivipelto M, Barbera M, MIND-AD and HATICE groups. Experiences of dementia and attitude towards prevention: a qualitative study among older adults participating in a prevention trial. BMC Geriatr. 2020 Mar 12;20(1):99. doi: 10.1186/s12877-020-1493-4.
  17. Ruiz JG, Dent E, Morley JE, Merchant RA, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer JM, Cesari M, Chen LK, Cruz-Jentoft AJ, De Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster JY, Rodriguez-Mañas L, Rolland Y, Sanford AM, Sinclair AJ, Viña J, Waters DL, Won Won C, Woo J, Vellas B. Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. J Nutr Health Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3.
  18. Soriano G, De Souto Barreto P, Virecoulon Giudici K, Cantet C, Guyonnet S, Vellas B, Rolland Y, Andrieu S; MAPT DSA Study Group. Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study [published online ahead of print, 2020 Mar 16]. Clin Nutr. 2020;S0261-5614(20)30114-X. doi: 1016/j.clnu.2020.03.011.
  19. van Wanrooij LL, Hoevenaar-Blom MP, Coley N, Ngandu T, Meiller Y, Guillemont J, Rosenberg A, Beishuizen CRL, Moll van Charante EP, Soininen H, Brayne C, Andrieu S, Kivipelto M, Richard E. Pooling individual participant data from randomized controlled trials: Exploring potential loss of information. PLoS One. 2020 May 12;15(5):e0232970. doi: 10.1371/journal.pone.0232970.
  20. Yu JT, Xu W, Tan CC, Andrieu S, Suckling J, Evangelou E, Pan A, Zhang C, Jia J, Feng L, Kua EH, Wang YJ, Wang HF, Tan MS, Li JQ, Hou XH, Wan Y, Tan L, Mok V, Tan L, Dong Q, Touchon J, Gauthier S, Aisen PS, Vellas B. Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. J Neurol Neurosurg Psychiatry. 2020 Nov;91(11):1201-1209. doi: 10.1136/jnnp-2019-321913.
2019
  1. Ancre Puymirat E, Cayla G, Cottin Y, Elbaz M, Henry P, Gerbaud E, Lemesle G, Popovic B, Labèque JN, Roubille F, Andrieu S, Farah B, Schiele F, Ferrières J, Simon T, Danchin N. Twenty-year trends in profile, management and outcomes of patients with ST-segment elevation myocardial infarction according to use of reperfusion therapy: Data from the FAST-MI program 1995-2015. Am Heart J. 2019 May 16;214:97-106. doi: 10.1016/j.ahj.2019.05.007.
  2. André L, Gallini A, Montastruc F, Coley N, Montastruc JL, Vellas B, Andrieu S, Gardette V; MAPT/DSA study group. Anticholinergic exposure and cognitive decline in older adults: effect of anticholinergic exposure definitions in a 3-year analysis of the multidomain Alzheimer preventive trial (MAPT) study. Br J Clin Pharmacol. 2019 Jan;85(1):71-99. doi: 10.1111/bcp.13734.
  3. Bowman GL, Dodge HH, Guyonnet S, Zhou N, Donohue J, Bichsel A, Schmitt J, Hooper C, Bartfai T, Andrieu S, Vellas B; MAPT/DSA Study Group. A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial. Alzheimers Dement (N Y). 2019;5:953–963. doi:10.1016/j.trci.2019.11.004.
  4. Coley N, Ngandu T, Lehtisalo J, Soininen H, Vellas B, Richard E, Kivipelto M, Andrieu S; HATICE, FINGER, and MAPT/DSA groups. Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials. Alzheimers Dement. 2019 Jun;15(6):729-741. doi: 10.1016/j.jalz.2019.0005.
  5. Coley N, Rosenberg A, van Middelaar T, Soulier A, Barbera M, Guillemont J, Steensma J, Igier V, Eskelinen M, Soininen H, Moll van Charante E, Richard E, Kivipelto M, Andrieu S; MIND-AD; HATICE groups. Older Adults' Reasons for Participating in an eHealth Prevention Trial: A Cross-Country, Mixed-Methods Comparison. J Am Med Dir Assoc. 2019 Jul;20(7):843-849.e5. doi: 10.1016/j.jamda.2018.10.019.
  6. Delrieu J, Payoux P, Carrié I, Cantet C, Weiner M, Vellas B, Andrieu S. Multidomain intervention and/or omega-3 in nondemented elderly subjects according to amyloid status. Alzheimers Dement. 2019 Nov;15(11):1392-1401. doi: 10.1016/j.jalz.2019.07.008.
  7. Gabelle A, Gutierrez LA, Jaussent I, Ben Bouallegue F, De Verbizier D, Navucet S, Grasselli C, Bennys K, Marelli C, David R, Mariano-Goulart D, Andrieu S, Vellas B, Payoux P, Berr C, Dauvilliers Y. Absence of Relationship Between Self-Reported Sleep Measures and Amyloid Load in Elderly Subjects. Front Neurol. Front Neurol. 2019 Sep 13;10:989. doi: 10.3389/fneur.2019.00989.
  8. Gabelle A, Jaussent I, Bouallègue FB, Lehmann S, Lopez R, Barateau L, Grasselli C, Pesenti C, de Verbizier D, Béziat S, Mariano-Goulart D, Carlander B, Dauvilliers Y; Alzheimer's Disease Neuroimaging Initiative; Multi-Domain Intervention Alzheimer's Prevention Trial study groups (Andrieu S collaborator). Reduced brain amyloid burden in elderly patients with narcolepsy type 1. Ann Neurol. 2019 Jan;85(1):74-83. doi: 10.1002/ana.25373.
  9. Gallini A, Yrondi A, Cantet C, Poncet M, Vellas B, Schmitt, Andrieu S. Red Blood Cell Omega-3 Fatty Acid Composition and Psychotropic Drug Use in Older Adults: Results from the MAPT Study. J Nutr Health Aging. 2019;23(9):805–812. doi: 10.1007/s12603-019-1252-4.
  10. Giudici KV, de Souto Barreto P, Guerville F, Beard J, Araujo de Carvalho I, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group. Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study). Exp Gerontol. 2019 Nov;127:110716. doi: 10.1016/j.exger.2019.110716.
  11. Herr M, Cesari M, Landre B, Ankri J, Vellas B, Andrieu S; MAPT/DSA Study Group. Factors associated with changes of the frailty status after age 70: Findings in the MAPT study. Ann Epidemiol. 2019 Jun;34:65-70.e1. doi:1016/j.annepidem.2019.03.008.
  12. Lilamand M, Cesari M, Cantet C, Andrieu S. Relationship between brain amyloid deposition and instrumental activities of daily living in older individuals: two analyses from the MAPT study. Geriatr Psychol Neuropsychiatr Vieil. 2019 Jun 1;17(2):211-220. doi: 10.1684/pnv.2019.0801.
  13. Maltais M, de Souto Barreto P, Pothier K, Cantet C, Andrieu S, Rolland Y, Vellas B; MAPT/DSA Study Group. Lifestyle multidomain intervention, omega-3 supplementation, or both for reducing the risk of developing clinically relevant depressive symptoms in older adults with memory complaints? Secondary analysis from the MAPT trial. Exp Gerontol. 2019 Jun;120:28-34. doi: 10.1016/j.exger.2019.02.010.
  14. Rolland Y, Barreto PS, Maltais M, Guyonnet S, Cantet C, Andrieu S, Vellas B. Effect of Long-Term Omega 3 Polyunsaturated Fatty Acid Supplementation with or without Multidomain Lifestyle Intervention on Muscle Strength in Older Adults: Secondary Analysis of the Multidomain Alzheimer Preventive Trial (MAPT). Nutrients. 2019 Aug 16;11(8):1931. doi: 10.3390/nu11081931.
  15. Rouch L, Cestac P, Hanon O, Ruidavets JB, Ehlinger V, Gentil C, Cool C, Helmer C, Dartigues JF, Bouhanick B, Chamontin B, Sallerin B, Vellas B, Marquié JC, Esquirol Y, Andrieu S. Blood pressure and cognitive performances in middle-aged adults: the Aging, Health and Work longitudinal study. J Hypertens. 2019 Jun;37(6):1244-1253. doi:10.1097/HJH.0000000000002013.
  16. Soriano G, De Barreto PS, Rolland Y, Plessz M, Goisser S, Guyonnet S, Fougère B, Vellas B, Andrieu S, Sourdet S; Groupe DSA MAPT. Ready-meal consumption in older people: association with obesity and dietary intake. Aging Clin Exp Res. 2019 Jun;31(6):855-861. doi: 10.1007/s40520-018-1043-5
  17. Vermunt L, Sikkes SAM, van den Hout A, Handels R, Bos I, van der Flier WM, Kern S, Ousset PJ, Maruff P, Skoog I, Verhey FRJ, Freund-Levi Y, Tsolaki M, Wallin ÅK, Olde Rikkert M, Soininen H, Spiru L, Zetterberg H, Blennow K, Scheltens P, Muniz-Terrera G, Visser PJ; Alzheimer Disease Neuroimaging Initiative; AIBL Research Group; ICTUS/DSA study groups (Andrieu S collaborator). Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype. Alzheimers Dement. 2019. 15 (7) : 888-898. doi: 10.1016/j.jalz.2019.04.001.