MAINTAIN - MAintain Functions and INTrinsec capacities with Aging :
Preventive and personalized INterventional Research

Equipe constitutive du CERPOP, UMR 1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
Philipe DE SOUTO BARRETO •  chercheur


2023

  1. Aragoni da Silva J, Rolland Y, Martinez LO, de Souto Barreto P. Mitochondrial Dysfunction and Intrinsic Capacity: Insights From a Narrative Review. J Gerontol A Biol Sci Med Sci. 2023 May 11;78(5):735-742. doi: 10.1093/gerona/glac227.
  2. Angioni D, Raffin J, Ousset PJ, Delrieu J, de Souto Barreto P. Fatigue in Alzheimer's disease: biological basis and clinical management-a narrative review. Aging Clin Exp Res. 2023 Jul 3. doi: 10.1007/s40520-023-02482-z.
  3. Bencivenga L, Strumia M, Rolland Y, Martinez L, Cestac P, Guyonnet S, Andrieu S, Parini A, Lucas A, Vellas B, De Souto Barreto P, Rouch L; MAPT/D. S. A. group. Biomarkers of mitochondrial dysfunction and inflammaging in older adults and blood pressure variability. Geroscience. 2023 Apr;45(2):797-809. doi: 10.1007/s11357-022-00697-y.
  4. de Souto Barreto P, Cesari M, Morley JE, Gonzalez-Bautista E, Rolland Y, Azzolino D, Vellas B, Fielding RA. Assessment and Management of Appetite Loss in Older Adults: An ICFSR Task Force Report. J Frailty Aging. 2023;12(1):1-6. doi: 10.14283/jfa.2022.64.
  5. de Souto Barreto P. Physical Activity, Exercise, and Sedentary Time: Insights for Future Research in the Field of Geroscience. JAR Life. 2023 Jun 8;12:20-22. doi: 10.14283/jarlife.2023.5.
  6. Gaussens L, González-Bautista E, Bonnefoy M, Briand M, Tavassoli N, De Souto Barreto P, Rolland Y, On Behalf Of The Gegn Group. Associations between Vitality/Nutrition and the Other Domains of Intrinsic Capacity Based on Data from the INSPIRE ICOPE-Care Program. Nutrients. 2023 Mar 24;15(7):1567. doi: 10.3390/nu15071567.
  7. Giudici KV, de Souto Barreto P, Guyonnet S, Morley JE, Nguyen AD, Aggarwal G, Parini A, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. TNFR-1 and GDF-15 Are Associated With Plasma Neurofilament Light Chain and Progranulin Among Community-Dwelling Older Adults: A Secondary Analysis of the MAPT Study. J Gerontol A Biol Sci Med Sci. 2023 Mar 30;78(4):569-578. doi: 10.1093/gerona/glac244.
  8. Giudici KV, de Souto Barreto P, Guyonnet S, Cantet C, Zetterberg H, Boschat C, Hudry J, Andrieu S, Schmitt JAJ, Vellas B, Blennow K; NOLAN/DSA group. Effect of a 1-Year Nutritional Blend Supplementation on Plasma p-tau181 and GFAP Levels among Community-Dwelling Older Adults: A Secondary Analysis of the Nolan Trial. JAR Life. 2023 Jun 12;12:25-34. doi: 10.14283/jarlife.2023.7.
  9. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique-Espinoza B, Sourdet S, Rolland Y, Rodríguez-Mañas L, Andrieu S, Vellas B; MAPT/DSA Group. Development and Validation of a Cutoff for the Chair Stand Test as a Screening for Mobility Impairment in the Context of the Integrated Care for Older People Program. J Gerontol A Biol Sci Med Sci. 2023 Jan 26;78(1):104-110. doi: 10.1093/gerona/glac055.
  10. Grande de França NA, Rolland Y, Guyonnet S, de Souto Barreto P. The role of dietary strategies in the modulation of hallmarks of aging. Ageing Res Rev. 2023 Jun;87:101908. doi: 10.1016/j.arr.2023.101908.
  11. Guion V, Sabra A, Martin C, Blanc E, De Souto Barreto P, Rolland Y. Pneumonia-Associated Emergency Transfers, Functional Decline, and Mortality in Nursing Home Residents. J Am Med Dir Assoc. 2023 May;24(5):747-752. doi: 10.1016/j.jamda.2023.02.108.
  12. Lengelé L, Sourdet S, Soriano G, Rolland Y, Soler V, de Souto Barreto P. Cross-sectional associations of dietary intake with hearing and vision capacities and potential mediation effect of inflammation in older adults: the COGFRAIL study. Aging Clin Exp Res. 2023 Jun;35(6):1325-1337. doi: 10.1007/s40520-023-02418-7.
  13. Lu WH, Gonzalez-Bautista E, Guyonnet S, Lucas A, Parini A, Walston JD, Vellas B, de Souto Barreto P; MAPT/DSA Group. Plasma inflammation-related biomarkers are associated with intrinsic capacity in community-dwelling older adults. J Cachexia Sarcopenia Muscle. 2023 Apr;14(2):930-939. doi: 10.1002/jcsm.13163.
  14. Raffin J, Rolland Y, Fischer C, Mangin JF, Gabelle A, Vellas B, de Souto Barreto P; MAPT/DSA Group. Cross-sectional associations between cortical thickness and physical activity in older adults with spontaneous memory complaints: The MAPT Study. J Sport Health Sci. 2023 May;12(3):324-332. doi: 10.1016/j.jshs.2021.01.011.
  15. Raffin J, de Souto Barreto P, Le Traon AP, Vellas B, Aubertin-Leheudre M, Rolland Y. Sedentary behavior and the biological hallmarks of aging. Ageing Res Rev. 2023 Jan;83:101807. doi: 10.1016/j.arr.2022.101807.
  16. Raffin J, Rolland Y, Parini A, Lucas A, Guyonnet S, Vellas B, de Souto Barreto P; MAPT/DSA Group. Association between physical activity, growth differentiation factor 15 and bodyweight in older adults: A longitudinal mediation analysis. J Cachexia Sarcopenia Muscle. 2023 Jan 20;14(2):771–80. doi: 10.1002/jcsm.13152. Epub ahead of prin
  17. Sánchez-Sánchez JL, Ader I, Jeanson Y, Planat-Benard V, Vellas B, Casteilla L, de Souto-Barreto P. Periostin Plasma Levels and Changes on Physical and Cognitive Capacities in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2023 Mar 1;78(3):424-432. doi:  10.1093/gerona/glac226.

2022

  1. Angioni D, Lu WH, Sourdet S, Macaron T, Takeda C, Guyonnet S, Mangin JF, Rolland Y, de Souto Barreto P, Vellas B. Biomarkers of Age-Related Frailty and Frailty Related to Diseases: An Exploratory, Cross-Sectional Analysis from the MAPT Study. J Nutr Health Aging. 2022;26(6):545-551. doi: 10.1007/s12603-022-1793-9.
  2. Bencivenga L, De Souto Barreto P, Rolland Y, Hanon O, Vidal JS, Cestac P, Vellas B, Rouch L. Blood pressure variability: A potential marker of aging. Ageing Res Rev. 2022 Sep;80:101677. doi: 10.1016/j.arr.2022.101677.
  3. Bullich S, de Souto Barreto P, Dortignac A, He L, Dray C, Valet P, Guiard BP. Apelin controls emotional behavior in age- and metabolic state-dependent manner. Psychoneuroendocrinology. 2022 Jun;140:105711. doi: 10.1016/j.psyneuen.2022.105711.
  4. Chrusciel J, Letty A, Armaingaud D, de Souto Barreto P, Berrut G, Rolland Y, Sanchez S. Factors predictive of adherence to a non-pharmacological intervention in nursing home research: a substudy of the LEDEN trial]. Geriatr Psychol Neuropsychiatr Vieil. 2022 Jun 1;20(2):199-207. doi: 10.1684/pnv.2022.1037.
  5. Damanti S, Tresoldi M, de Souto Barreto P, Rolland Y, Cesari M. Z-drugs and falls in nursing home patients: data from the INCUR study. Aging Clin Exp Res. 2022 Dec;34(12):3145-3149. doi: 10.1007/s40520-022-02237-2.
  6. de Souto Barreto P. Editorial: Poor Appetite and Aging: The Role of Physical Activity under a Geroscience Perspective. J Nutr Health Aging. 2022;26(10):907-908. doi: 10.1007/s12603-022-1849-x.
  7. de Souto Barreto P, Cesari M, Morley JE, Roberts S, Landi F, Cederholm T, Rolland Y, Vellas B, Fielding R. Appetite Loss and Anorexia of Aging in Clinical Care: An ICFSR Task Force Report. J Frailty Aging. 2022;11(2):129-134. doi: 10.14283/jfa.2022.14.
  8. de Souto Barreto P, Fabre D, Vellas B, Blain H, Molinier L, Rolland Y. Reduction prevalence of fragility fracture hospitalisation during the COVID-19 lockdown. Arch Osteoporos. 2022 Apr 18;17(1):68. doi: 10.1007/s11657-022-01099-5.
  9. de Souto Barreto P, Ruiz JG, Merchant RA. Editorial: Journal of Nutrition, Health and Aging: Summary of Recent Work and Future Directions. J Nutr Health Aging. 2022;26(1):1-2. doi: 10.1007/s12603-022-1725-8.
  10. Díaz G, Lengele L, Sourdet S, Soriano G, de Souto Barreto P. Nutrients and amyloid β status in the brain: A narrative review. Ageing Res Rev. 2022 Nov;81:101728. doi: 10.1016/j.arr.2022.101728.
  11. Dubucs X, Balen F, Charpentier S, Lauque D, De Souto Barreto P, Tavassoli N, Houze-Cerfon CH, Rolland Y. Factors associated with Emergency Medical Dispatcher request and residents' inappropriate transfers from Nursing Homes to Emergency Department. Eur Geriatr Med. 2022 Apr;13(2):351-357. doi: 10.1007/s41999-021-00574-5.
  12. Fougère B, Goisser S, Cantet C, Soriano G, Guyonnet S, De Souto Barreto P, Cesari M, Andrieu S, Vellas B; MAPT Study Group. Retraction Note to: Omega-3 fatty acid levels in red blood cell membranes and physical decline over 3 years: longitudinal data from the MAPT study. Geroscience. 2022 Apr;44(2):1173. doi: 10.1007/s11357-021-00505-z.
  13. Giudici KV, Guyonnet S, Cantet C, de Souto Barreto P, Weiner MW, Tosun D, Boschat C, Hudry J, Andrieu S, Vellas B, Schmitt JAJ; Nolan/DSA group. A 1-year randomized controlled trial of a nutritional blend to improve nutritional biomarkers and prevent cognitive decline among community-dwelling older adults: The Nolan Study. Alzheimers Dement (N Y). 2022 Sep 28;8(1):e12314. doi: 10.1002/trc2.12314.
  14. Giudici KV, Guyonnet S, Morley JE, Nguyen AD, Aggarwal G, Parini A, Li Y, Bateman RJ, Vellas B, de Souto Barreto P; MAPT/DSA Group. Interactions Between Weight Loss and Plasma Neurodegenerative Markers for Determining Cognitive Decline Among Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2022 Jun 1;77(6):1159-1168. doi: 10.1093/gerona/glac015.
  15. Gonçalves RSDSA, Maciel ÁCC, Rolland Y, Vellas B, de Souto Barreto P. Frailty biomarkers under the perspective of geroscience: A narrative review. Ageing Res Rev. 2022 Nov;81:101737. doi: 10.1016/j.arr.2022.101737.
  16. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique-Espinoza B, Rolland Y, Andrieu S, Vellas B; MAPT/DSA group. Clinically meaningful change for the chair stand test: monitoring mobility in integrated care for older people. J Cachexia Sarcopenia Muscle. 2022 Oct;13(5):2331-2339. doi: 10.1002/jcsm.13042.
  17. Guion V, De Souto Barreto P, Cesari M, Rolland Y. Quality of Life and Pneumonia in Nursing Home Residents: A 1-Year Observational Study. J Am Med Dir Assoc. 2022 Oct;23(10):1736-1740. doi: 10.1016/j.jamda.2022.06.018.
  18. He L, de Souto Barreto P, Sánchez Sánchez JL, Rolland Y, Guyonnet S, Parini A, Lucas A, Vellas B; MAPT/DSA Group. Prospective associations of plasma growth differentiation factor 15 with physical performance and cognitive functions in older adults. J Gerontol A J Gerontol A Biol Sci Med Sci. 2022 Dec 29;77(12):2420-2428. doi: 10.1093/gerona/glac020.
  19. Lu WH, Giudici KV, Guyonnet S, Aggarwal G, Nguyen AD, Morley JE, Vellas B, de Souto Barreto P; MAPT/DSA Group. Associations of plasma neurofilament light chain and progranulin with frailty in older adults. J Am Geriatr Soc. 2022 Apr;70(4):1236-1243. doi: 10.1111/jgs.17604.
  20. Lu WH, Giudici KV, Morley JE, Guyonnet S, Parini A, Aggarwal G, Nguyen AD, Li Y, Bateman RJ, Vellas B, de Souto Barreto P; MAPT/DSA Group. Investigating the combination of plasma amyloid-beta and geroscience biomarkers on the incidence of clinically meaningful cognitive decline in older adults. Geroscience. 2022 Jun;44(3):1489-1503. doi: 10.1007/s11357-022-00554-y.
  21. Lu WH, Vellas B, de Souto Barreto P. Reply to: Comment on: The associations of plasma neurofilament light chain and progranulin with frailty in older adults. J Am Geriatr Soc. 2022 Jul;70(7):2169-2170. doi: 10.1111/jgs.17782.
  22. Maltais M, de Souto Barreto P, Bowman GL, Smith AD, Cantet C, Andrieu S, Rolland Y. Omega-3 Supplementation for the Prevention of Cognitive Decline in Older Adults: Does It Depend on Homocysteine Levels? J Nutr Health Aging. 2022;26(6):615-620. doi: 10.1007/s12603-022-1809-5.
  23. Molet-Benhamou L, Giudici KV, de Souto Barreto P, Cantet C, Rolland Y; MAPT/DSA group. Association between urate-lowering therapies and cognitive decline in community-dwelling older adults. Sci Rep. 2022 Sep 12;12(1):15299. doi: 10.1038/s41598-022-17808-6.
  24. Pagès A, Costa N, González-Bautista E, Mounié M, Juillard-Condat B, Molinier L, Cestac P, Rolland Y, Vellas B, De Souto Barreto P; MAPT/DSA Group. Screening for deficits on intrinsic capacity domains and associated healthcare costs. Arch Gerontol Geriatr. 2022 May-Jun;100:104654. doi: 10.1016/j.archger.2022.104654.
  25. Pagès A, Costa N, Mounié M, Cestac P, De Souto Barreto P, Rolland Y, Vellas B, Molinier L, Juillard-Condat B; MAPT/DSA Group. Healthcare Costs Associated with Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm Among Older Patients. Drugs Aging. 2022 May;39(5):367-375. doi: 10.1007/s40266-022-00938-x.
  26. Raffin J, Angioni D, Giudici KV, Valet P, Aggarwal G, Nguyen AD, Morley JE, Guyonnet S, Rolland Y, Vellas B, de Souto Barreto P; MAPT/DSA Group. Physical Activity, Body Mass Index, and Blood Progranulin in Older Adults: Cross-Sectional Associations in the MAPT Study. J Gerontol A Biol Sci Med Sci. 2022 Jun 1;77(6):1141-1149. doi: 10.1093/gerona/glac018.
  27. Sanchez-Sanchez JL, Giudici KV, Guyonnet S, Delrieu J, Li Y, Bateman RJ, Parini A, Vellas B, de Souto Barreto P; MAPT/DSA Group. Plasma MCP-1 and changes on cognitive function in community-dwelling older adults. Alzheimers Res Ther. 2022 Jan 7;14(1):5. doi: 10.1186/s13195-021-00940-2.
  28. Sanchez-Sanchez JL, He L, Virecoulon Giudici K, Guyonnet S, Parini A, Dray C, Valet P, Pereira O, Vellas B, Rolland Y, de Souto Barreto P. Circulating Levels of Apelin, GDF-15 and Sarcopenia: Lack of Association in the MAPT Study. J Nutr Health Aging. 2022;26(6):564-570. doi: 10.1007/s12603-022-1800-1.
  29. Sánchez-Sánchez JL, Rolland Y, Cesari M, de Souto Barreto P. Associations Between Intrinsic Capacity and Adverse Events Among Nursing Home Residents: The INCUR Study. J Am Med Dir Assoc. 2022 May;23(5):872-876.e4. doi: 10.1016/j.jamda.2021.08.035.
  30. Sánchez-Sánchez JL, Ader I, Jeanson Y, Planat-Benard V, Vellas B, Casteilla L, de Souto-Barreto P. Periostin plasma levels and changes on physical and cognitive capacities in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2022 Nov 14:glac226. doi: 10.1093/gerona/glac226.
  31. Sánchez-Sánchez JL, Rolland Y, Cesari M, de Souto Barreto P. Impact of nursing home-acquired pneumonia on the domains of the novel construct of intrinsic capacity: the INCUR study. J Am Geriatr Soc. 2022 Dec;70(12):3436-3446. doi: 10.1111/jgs.17991.
  32. Tavassoli N, de Souto Barreto P, Berbon C, Mathieu C, de Kerimel J, Lafont C, Takeda C, Carrie I, Piau A, Jouffrey T, Andrieu S, Nourhashemi F, Beard JR, Soto Martin ME, Vellas B. Implementation of the WHO integrated care for older people (ICOPE) programme in clinical practice: a prospective study. Lancet Healthy Longev. 2022 Jun;3(6):e394-e404. doi: 10.1016/S2666-7568(22)00097-6.

2021

  1. Angioni D, Virecoulon Giudici K, Montoya Martinez M, Rolland Y, Vellas B, de Souto Barreto P. Neuroimaging markers of chronic fatigue in older people: a narrative review. Aging Clin Exp Res. 2021 Jun;33(6):1487-1492. doi: 10.1007/s40520-020-01666-1.
  2. Angioni D, Cesari M, Raffin J, Virecoulon Giudici K, Mangin JF, Bouyahia A, Chupin M, Fischer C, Gourieux E, Rolland Y, De Breucker S, Vellas B, de Souto Barreto P; MAPT/DSA group. Neuroimaging correlates of persistent fatigue in older adults: A secondary analysis from the Multidomain Alzheimer Preventive Trial (MAPT) trial. Aging Ment Health. 2022 Aug;26(8):1654-1660. . doi: 10.1080/13607863.2021.1932737.
  3. Azzolino D, Marzetti E, Proietti M, Calvani R, de Souto Barreto P, Rolland Y, Cesari M. Lack of energy is associated with malnutrition in nursing home residents: Results from the INCUR study. J Am Geriatr Soc. 2021 Nov;69(11):3242-3248.. doi: 10.1111/jgs.17393.
  4. Damanti S, de Souto Barreto P, Rolland Y, Astrone P, Cesari M. Malnutrition and physical performance in nursing home residents: results from the INCUR study. Aging Clin Exp Res. 2021 Aug;33(8):2299-2303. doi: 10.1007/s40520-021-01798-y.
  5. de Souto Barreto P, Guyonnet S, Ader I, Andrieu S, Casteilla L, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Rolland Y, Valet P, Vergnolle N, Vellas B. The INSPIRE Research Initiative: A Program for GeroScience and Healthy Aging Research Going from Animal Models to Humans and the Healthcare System. J Frailty Aging. 2021;10(2):86-93. doi: 10.14283/jfa.2020.18.
  6. de Souto Barreto P, Maltais M, Rosendahl E, Vellas B, Bourdel-Marchasson I, Lamb SE, Pitkala K, Rolland Y. Exercise Effects on Falls, Fractures, Hospitalizations, and Mortality in Older Adults With Dementia: An Individual-Level Patient Data Meta-analysis. J Gerontol A Biol Sci Med Sci. 2021 Aug 13;76(9):e203-e212. doi: 10.1093/gerona/glaa307.
  7. de Souto Barreto P, Rolland Y. Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined. N Engl J Med. 2021 Aug 5;385(6):572. doi: 10.1056/NEJMc2109509.
  8. de Souto Barreto P, Vellas B, Rolland Y. Physical activity and exercise in the context of SARS-Cov-2: A perspective from geroscience field. Ageing Res Rev. 2021 Mar;66:101258. doi: 10.1016/j.arr.2021.101258.
  9. Damanti S, de Souto Barreto P, Rolland Y, Astrone P, Cesari M. Malnutrition and physical performance in nursing home residents: results from the INCUR study. Aging Clin Exp Res. 2021 Aug;33(8):2299-2303. doi: 10.1007/s40520-021-01798-y.
  10. González-Bautista E, de Souto Barreto P, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group (members are listed under ‘Contributors’). Screening for intrinsic capacity impairments as markers of increased risk of frailty and disability in the context of integrated care for older people: Secondary analysis of MAPT. Maturitas. 2021 Aug;150:1-6. doi: 10.1016/j.maturitas.2021.05.011.
  11. González-Bautista E, de Souto Barreto P, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group. What day is today? Cognitive capacity and the risk of incident dementia in the context of integrated care for older people (ICOPE Step 1). Aging Clin Exp Res. 2021 Feb 13. doi: 10.1007/s40520-021-01803-4.
  12. González-Bautista E, de Souto Barreto P, Virecoulon Giudici K, Andrieu S, Rolland Y, Vellas B. Frequency of Conditions Associated with Declines in Intrinsic Capacity According to a Screening Tool in the Context of Integrated Care for Older People. J Frailty Aging. 2021;10(2):94-102. doi: 10.14283/jfa.2020.42.
  13. Guerville F, De Souto Barreto P, Coley N, Andrieu S, Mangin JF, Chupin M, Payoux P, Ousset PJ, Rolland Y, Vellas B; MAPT/DSA group. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration. J Am Geriatr Soc. 2021 Mar;69(3):651-659. doi: 10.1111/jgs.16954.
  14. Guion V, De Souto Barreto P, Rolland Y. Nursing Home Residents' Functional Trajectories and Mortality After a Transfer to the Emergency Department. J Am Med Dir Assoc. 2021 Feb;22(2):393-398.e3. doi: 10.1016/j.jamda.2020.05.033.
  15. Guion V, de Souto Barreto P, Rolland Y. Trajectories of Symptoms in Nursing Home Residents after a Transfer to the Emergency Department. J Nutr Health Aging. 2021;25(3):318-324. doi: 10.1007/s12603-020-1476-3.
  16. Guyonnet S, Rolland Y, Takeda C, Ousset PJ, Ader I, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Valet P, Vergnolle N, Andrieu S, de Souto Barreto P, Casteilla L, Vellas B. The INSPIRE Bio-Resource Research Platform for Healthy Aging and Geroscience: Focus on the Human Translational Research Cohort (The INSPIRE-T Cohort). J Frailty Aging. 2021;10(2):110-120. doi: 10.14283/jfa.2020.38.
  17. He L, de Souto Barreto P, Giudici KV, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Cross-Sectional and Longitudinal Associations Between Plasma Neurodegenerative Biomarkers and Physical Performance Among Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2021 Sep 13;76(10):1874-1881. doi: 10.1093/gerona/glaa284.
  18. He L, de Souto Barreto P, Giudici KV, Gabelle A, Perus L, Mangin JF, Rolland Y, Vellas B; Other Individuals in the MAPT/DSA Group. Five-Year Lower Extremity Function is Associated with White Matter Abnormality in Older Adults. J Am Geriatr Soc. 2021 Apr;69(4):995-1002. doi: 10.1111/jgs.16989.
  19. He L, Morley JE, Aggarwal G, Nguyen AD, Vellas B, de Souto Barreto P; MAPT/DSA Group. Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults. Sci Rep. 2021 Jun 28;11(1):13394. doi: 10.1038/s41598-021-91038-0.
  20. Izquierdo M, Merchant RA, Morley JE, Anker SD, Aprahamian I, Arai H, Aubertin-Leheudre M, Bernabei R, Cadore EL, Cesari M, Chen LK, de Souto Barreto P, Duque G, Ferrucci L, Fielding RA, García-Hermoso A, Gutiérrez-Robledo LM, Harridge SDR, Kirk B, Kritchevsky S, Landi F, Lazarus N, Martin FC, Marzetti E, Pahor M, Ramírez-Vélez R, Rodriguez-Mañas L, Rolland Y, Ruiz JG, Theou O, Villareal DT, Waters DL, Won Won C, Woo J, Vellas B, Fiatarone Singh M. International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines. J Nutr Health Aging. 2021;25(7):824-853. doi: 10.1007/s12603-021-1665-8.
  21. Lu WH, de Souto Barreto P, Rolland Y, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group (Abellan van Kan G, Cantet C, Delrieu J, Guyonnnet  S, Ousset PJ, Villars H, Voisin T collaborators). Biological and Neuroimaging Markers as Predictors of 5-Year Incident Frailty in Older Adults: A Secondary Analysis of the MAPT Study. J Gerontol A Biol Sci Med Sci. 2021 Oct 13;76(11):e361-e369. doi: 10.1093/gerona/glaa296.
  22. Lu WH, Giudici KV, Rolland Y, Guyonnet S, Li Y, Bateman RJ, de Souto Barreto P, Vellas B. Prospective Associations between Plasma Amyloid-Beta 42/40 and Frailty in Community-Dwelling Older Adults. J Prev Alzheimers Dis. 2021;8(1):41-47. doi: 10.14283/jpad.2020.60.
  23. Lu WH, Giudici KV, Rolland Y, Guyonnet S, Mangin JF, Vellas B, de Souto Barreto P. Associations Between Nutritional Deficits and Physical Performance in Community-Dwelling Older Adults. Front Nutr. 2021 Nov 11;8:771470. doi: 10.3389/fnut.2021.771470.
  24. Macaron T, Giudici KV, Bowman GL, Sinclair A, Stephan E, Vellas B, de Souto Barreto P. Associations of Omega-3 fatty acids with brain morphology and volume in cognitively healthy older adults: A narrative review. Ageing Res Rev. 2021 May;67:101300. doi: 10.1016/j.arr.2021.101300.
  25. Pagès A, Rouch L, Costa N, Cestac P, de Souto Barreto P, Rolland Y, Vellas B, Molinier L, Juillard-Condat B, Mapt/Dsa Group. Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm among Older Patients: Results from the MAPT Study. Pharmacy (Basel). 2021 Nov 24;9(4):189. doi: 10.3390/pharmacy9040189.
  26. Raffin J, Rolland Y, He L, Perus L, Mangin JF, Gabelle A, Virecoulon Giudici K, Vellas B, de Souto Barreto P; MAPT/DSA Group. Cross-sectional and longitudinal interaction effects of physical activity and APOE-ε4 on white matter integrity in older adults: The MAPT study. Maturitas. 2021 Oct;152:10-19. doi: 10.1016/j.maturitas.2021.06.010.
  27. Rolland Y, Mathieu C, Tavassoli N, Berard E, Laffon de Mazières C, Hermabessière S, Houles M, Perrin A, Krams T, Qassemi S, Cambon A, Magre E, Cantet C, Charpentier S, Lauque D, Azema O, Chicoulaa B, Oustric S, McCambridge C, Gombault-Datzenko E, Molinier L, Costa N, De Souto Barreto P. Factors Associated with Potentially Inappropriate Transfer to the Emergency Department among Nursing Home Residents. J Am Med Dir Assoc. 2021 Dec;22(12):2579-2586.e7. doi: 10.1016/j.jamda.2021.04.002.
  28. Rouch L, de Souto Barreto P, Hanon O, Vidal JS, Amar J, Andrieu S, Cestac P, Rolland Y, Vellas B; MAPT/DSA Group. Visit-to-Visit Blood Pressure Variability and Incident Frailty in Older Adults. J Gerontol A Biol Sci Med Sci. 2021 Jul 13;76(8):1369-1375. doi: 10.1093/gerona/glab112.
  29. Rouch L, Rolland Y, Hanon O, Vidal JS, Cestac P, Sallerin B, Andrieu S, Vellas B, de Souto Barreto P; MAPT/DSA Group. Blood pressure, antihypertensive drugs, and incident frailty: The Multidomain Alzheimer Preventive Trial (MAPT). Maturitas. 2022 Aug;162:8-14. doi: 10.1016/j.maturitas.2022.03.001.
  30. Santin Y, Lopez S, Ader I, Andrieu S, Blanchard N, Carrière A, Casteilla L, Cousin B, Davezac N, De Souto Barreto P, Dray C, Fazilleau N, Gonzalez-Dunia D, Gourdy P, Guyonnet S, Jabrane-Ferrat N, Kunduzova O, Lezoualc'h F, Liblau R, Martinez LO, Moro C, Payoux P, Pénicaud L, Planat-Bénard V, Rampon C, Rolland Y, Schanstra JP, Sierra F, Valet P, Varin A, Vergnolle N, Vellas B, Viña J, Guiard BP, Parini A. Towards a Large-Scale Assessment of the Relationship between Biological and Chronological Aging: The INSPIRE Mouse Cohort. J Frailty Aging. 2021;10(2):121-131. doi: 10.14283/jfa.2020.43.
  31. Simo N, Cesari M, Tchiero H, Rolland Y, de Souto Barreto P, Dartigues JF, Vellas B, Tabue-Teguo M. Frailty Index, Hospital Admission and Number of Days Spent in Hospital in Nursing Home Residents: Results from the Incur Study. J Nutr Health Aging. 2021;25(2):155-159. doi: 10.1007/s12603-020-1561-7.
  32. Tavassoli N, Piau A, Berbon C, De Kerimel J, Lafont C, De Souto Barreto P, Guyonnet S, Takeda C, Carrie I, Angioni D, Paris F, Mathieu C, Ousset PJ, Balardy L, Voisin T, Sourdet S, Delrieu J, Bezombes V, Pons-Pretre V, Andrieu S, Nourhashemi F, Rolland Y, Soto ME, Beard J, Sumi Y, Araujo Carvalho I, Vellas B. Framework Implementation of the INSPIRE ICOPE-CARE Program in Collaboration with the World Health Organization (WHO) in the Occitania Region. J Frailty Aging. 2021;10(2):103-109. doi: 10.14283/jfa.2020.26.

2020

  1. Angioni D, Macaron T, Takeda C, Sourdet S, Cesari M, Virecoulon Giudici K, Raffin J, Lu WH, Delrieu J, Touchon J, Rolland Y, de Souto Barreto P, Vellas B. Can We Distinguish Age-Related Frailty from Frailty Related to Diseases ? Data from the MAPT Study. J Nutr Health Aging. 2020;24(10):1144-1151. doi: 10.1007/s12603-020-1518-x.
  2. Angioni D, Virecoulon Giudici K, Montoya Martinez M, Rolland Y, Vellas B, de Souto Barreto P. Neuroimaging markers of chronic fatigue in older people: a narrative review. Aging Clin Exp Res. 2020 Jul 30. doi: 10.1007/s40520-020-01666-1. Epub ahead of print.
  3. El Haddad K, Rolland Y, Gérard S, Mourey L, Sourdet S, Vellas B, Stephan E, Abellan Van Kan G, de Souto Barreto P, Balardy L. No Difference in the Phenotypic Expression of Frailty among Elderly Patients Recently Diagnosed with Cancer Vs Cancer Free Patients. J Nutr Health Aging. 2020;24(2):147–151. doi: 10.1007/s12603-019-1293-8.
  4. El Haddad K, de Souto Barreto P, de Mazieres CL, Rolland Y. Effect of a geriatric intervention aiming to improve polypharmacy in nursing homes. Eur Geriatr Med. 2020 Oct;11(5):863-868. doi: 10.1007/s41999-019-00279-w.
  5. El Haddad K, Rolland Y, Gérard S, Mourey L, Sourdet S, Vellas B, Stephan E, Abellan Van Kan G, de Souto Barreto P, Balardy L. No Difference in the Phenotypic Expression of Frailty among Elderly Patients Recently Diagnosed with Cancer Vs Cancer Free Patients. J Nutr Health Aging. 2020;24(2):147–151. doi:10.1007/s12603-019-1293-8.
  6. Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B. Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. J Prev Alzheimers Dis. 2020;7(1):56–64. doi: 10.14283/jpad.2019.50.
  7. Guerville F, De Souto Barreto P, Coley N, Andrieu S, Mangin JF, Chupin M, Payoux P, Ousset PJ, Rolland Y, Vellas B; MAPT/DSA group. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration. J Am Geriatr Soc. 2020 Nov 20. doi: 10.1111/jgs.16954.
  8. Giudici KV, de Souto Barreto P, Beard J, Cantet C, Araujo de Carvalho I, Rolland Y, Vellas B; MAPT DSA group. Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study). Maturitas. 2020 Nov;141:39-45. doi: 10.1016/j.maturitas.2020.06.012.
  9. Giudici KV, de Souto Barreto P, Guyonnet S, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults. JAMA Netw Open. 2020 Dec 1;3(12):e2028634. doi: 10.1001/jamanetworkopen.2020.28634.
  10. He L, de Souto Barreto P, Giudici KV, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Cross-sectional and longitudinal associations between plasma neurodegenerative biomarkers and physical performance among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2020 Nov 13:glaa284. doi: 10.1093/gerona/glaa284. Epub ahead of print.
  11. Hooper C, Coley N, de Souto Barreto P, Payoux P, Salabert AS, Andrieu S, Weiner M, Vellas B. Cortical β-Amyloid in Older Adults Is Associated with Multidomain Interventions with and without Omega 3 Polyunsaturated Fatty Acid Supplementation. J Prev Alzheimers Dis. 2020;7(2):128–134. doi: 10.14283/jpad.2020.4.
  12. Lu WH, de Souto Barreto P, Rolland Y, Rodríguez-Mañas L, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Cross-sectional and prospective associations between cerebral cortical thickness and frailty in older adults. Exp Gerontol. 2020 Oct 1;139:111018. doi: 10.1016/j.exger.2020.111018. Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group. Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 May;68(5):1050-1055. doi: 10.1111/jgs.16343.
  13. Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B. Re: Prospective Associations between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 Apr 16. doi: 10.1111/jgs.16456. Epub ahead of print.
  14. Maltais M, Rolland Y, Boisvert-Vigneault K, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Vellas B, de Souto Barreto P.. Prospective associations between physical activity levels and white matter integrity in older adults: results from the MAPT study. Maturitas. 2020;137:24-29. doi: 10.1016/j.maturitas.2020.04.012.
  15. Masciocchi E, Maltais M, El Haddad K, Virecoulon Giudici K, Rolland Y, Vellas B, de Souto Barreto P. Defining Vitality Using Physical and Mental Well-Being Measures in Nursing Homes: A Prospective Study. J Nutr Health Aging. 2020;24(1):37-42. doi: 10.1007/s12603-019-1285-8.
  16. Parrotta I, De Mauleon A, Abdeljalil AB, de Souto Barreto P, Lethin C, Veerbek H, Stephan A, Saks K, Zabalegui A, Soto Martin ME. Depression in People With Dementia and Caregiver Outcomes: Results From the European Right Time Place Care Study. J Am Med Dir Assoc. 2020;21(6):872-878.e1. doi:10.1016/j.jamda.2020.02.023.
  17. Rolland Y, Lacoste MH, de Mauleon A, Ghisolfi A, de Souto Barreto P, Blain H, Villars H. Guidance for the Prevention of the COVID-19 Epidemic in Long-Term Care Facilities: A Short-Term Prospective Study. J Nutr Health Aging. 2020;24(8):812-816. doi: 10.1007/s12603-020-1440-2.
  18. Rolland Y, Tavassoli N, de Souto Barreto P, Perrin A , Laffon de Mazières C, Rapp T, Hermabessière S, Tournay E, Vellas B, Andrieu S. Systematic Dementia Screening by Multidisciplinary Team Meetings in Nursing Homes for Reducing Emergency Department Transfers: The IDEM Cluster Randomized Clinical Trial. JAMA Netw Open. 2020 Feb 5;3(2):e200049. doi: 10.1001/jamanetworkopen.2020.0049.
  19. Ruiz JG, Dent E, Morley JE, Merchant RA, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer JM, Cesari M, Chen LK, Cruz-Jentoft AJ, de Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster JY, Rodriguez-Mañas L, Rolland Y, Sanford AM, Sinclair AJ, Viña J, Waters DL, Won Won C, Woo J, Vellas B. Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. J Nutr Health Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3.
  20. Takeda C, Angioni D, Setphan E, Macaron T, de Souto Barreto P, Sourdet S, Sierra F, Vellas B. Age-Related Frailty: A Clinical Model for Geroscience? J Nutr Health Aging. 2020;24(10):1140-1143. doi: 10.1007/s12603-020-1491-4.
  21. Soriano G, de Souto Barreto P, Virecoulon Giudici K, Cantet C , Guyonnet S, Vellas B , Rolland Y , Andrieu S , MAPT DSA Study Group. Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study. Clin Nutr. 2020 Nov;39(11):3483-3488. doi: 10.1016/j.clnu.2020.03.011.
  22. Vellas C, Delobel P, de Souto Barreto P, Izopet J. COVID-19, Virology and Geroscience: A Perspective. J Nutr Health Aging. 2020;24(7):685-691. doi: 10.1007/s12603-020-1416-2.
 

2019

  1. de Souto Barreto P, Rolland Y, Vellas B, Maltais M. Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults: A Systematic Review and Meta-analysis. JAMA Intern Med. 2019. 179 (3), 394-405. doi: 10.1001/jamainternmed.2018.5406.
  2. Dubucs X, de Souto Barreto P, Laffon de Mazieres C, Lauque D, Azema O, Charpentier S, Rolland Y. The Temporal Trend in the Transfer of Older Adults to the Emergency Department for Traumatic Injuries: A Retrospective Analysis According to Their Place of Residence. J Am Med Dir Assoc. 2019. 20(11):1462-1466. doi: 10.1016/j.jamda.2019.07.013.
  3. Girard P, Sourdet S, Cantet C, de Souto Barreto P, Rolland Y. Acetaminophen Safety: Risk of Mortality and Cardiovascular Events in Nursing Home Residents, a Prospective Study. J Am Geriatr Soc. 2019. 67(6):1240-1247. doi: 10.1111/jgs.1586
  4. Giudici KV, de Souto Barreto P, Guerville F, Beard J, Araujo de Carvalho I, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group. Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study). Exp Gerontol. 2019 Nov;127:110716. doi: 10.1016/j.exger.2019.110716.
  5. Giudici KV, de Souto Barreto P, Soriano G, Rolland Y, Vellas B. Defining Vitality: Associations of Three Operational Definitions of Vitality with Disability in Instrumental Activities of Daily Living and Frailty among Elderly Over a 3-Year Follow-Up (MAPT Study). J Nutr Health Aging. 2019. 23(4):386-392. doi: 10.1007/s12603-019-1175-0.
  6. Giudici KV, Guyonnet S, Rolland Y, Vellas B, de Souto Barreto P, Nourhashemi F; MAPT/DSA Group. Body Weight Variation Patterns as Predictors of Cognitive Decline over a 5 Year Follow-Up among Community-Dwelling Elderly (MAPT Study). Nutrients. 2019 Jun 18;11(6):1371. doi: 10.3390/nu11061371.
  7. Guerville F, de Souto Barreto P, Giudici KV, Rolland Y, Vellas B; MAPT/DSA Group. Association of 3-Year Multidomain Intervention and Omega-3 Supplementation with Frailty Incidence. J Am Geriatr Soc. 2019. 67 (8), 1700-1706. doi: 10.1111/jgs.15994.
  8. Guerville F, de Souto Barreto P, Taton B, Bourdel-Marchasson I, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial (MAPT)/Data Sharing Alzheimer (DSA) Group. Estimated Glomerular Filtration Rate Decline and Incident Frailty in Older Adults. Clin J Am Soc Nephrol. 2019 Nov 7;14(11):1597-1604. doi: 10.2215/CJN.03750319.
  9. Maltais M, Boisvert-Vigneault K, Rolland Y, Vellas B, de Souto Barreto P; MAPT/DSA Study Group. Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The MAPT study. Exp Gerontol. 2019 Dec;128:110758. doi: 10.1016/j.exger.2019.110758.
  10. Maltais M, de Souto Barreto P, Hooper C, Payoux P, Rolland Y, Vellas B; MAPT/DSA Study Group. Association between brain b-amyloid and frailty in older adults. J Gerontol A Biol Sci Med Sci. 2019. 74 (11), 1747-175 doi: 10.1093/gerona/glz009.
  11. Maltais M, de Souto Barreto P, Moon SY, Rolland Y, Vellas B; MAPT/DSA Study Group. Prospective association of white matter hyperintensity volume and frailty in older adults. Exp Gerontol. 2019 Apr;118:51-54. doi: 10.1016/j.exger.2019.01.007.
  12. Maltais M, de Souto Barreto P, Pothier K, Cantet C, Andrieu S, Rolland Y, Vellas B; MAPT/DSA Study Group. Lifestyle multidomain intervention, omega-3 supplementation, or both for reducing the risk of developing clinically relevant depressive symptoms in older adults with memory complaints? Secondary analysis from the MAPT trial. Exp Gerontol. 2019 Jun;120:28-3 doi: 10.1016/j.exger.2019.02.010.
  13. Maltais M, de Souto Barreto P, Rolland Y, Vellas B. Is Fat Mass Cross-Sectionally Associated with Cortical Aβ Load in the Human Brain? J Nutr Health Aging. 2019;23(2):207-210. doi: 10.1007/s12603-018-1121-6.
  14. Maltais M, de Souto Barreto P, Rolland Y, Vellas B. The Association of ApoE ε4 Status with Lower Limb Function and Handgrip Strength in Older Adults. J Frailty Aging. 2019;8(2):62-6 doi: 10.14283/jfa.2019.7.
  15. Maltais M, Rolland Y, Haÿ PE, Armaingaud D, Vellas B, de Souto Barreto P. Six-month observational follow-up on activities of daily living in people with dementia living in nursing homes after a 6-month group based on either exercise or social activities. Aging Clin Exp Res. 2019 Mar;31(3):361-366. doi: 10.1007/s40520-018-0984-z.
  16. Maltais M, Rolland Y, Vellas B, Haÿ PE, Armaingaud D, Cestac P, Rouch L, Cesari M, de Souto Barreto P. Effect of Exercise on Behavioral Symptoms and Pain in Patients With Dementia Living in Nursing Homes. Am J Alzheimers Dis Other Demen. 2019 Mar;34(2):89-94. doi: 10.1177/1533317518803773.
  17. Masciocchi E, Maltais M, Rolland Y, Vellas B, de Souto Barreto P. Time Effects on Physical Performance in Older Adults in Nursing Home: A Narrative Review. J Nutr Health Aging. 2019;23(6):586-594: doi: 10.1007/s12603-019-1199-5.
  18. Parrotta I, Maltais M, Rolland Y, Spampinato DA, Robert P, de Souto Barreto P, Vellas B; MAPT/DSA group. The association between apathy and frailty in older adults: a new investigation using data from the Mapt study. Aging Ment Health. 2019 Aug 14:1-5. doi: 10.1080/13607863.2019.1650890.
  19. Pothier K, Saint-Aubert L, Hooper C, Delrieu J, Payoux P, de Souto Barreto P, Vellas B; MAPT/DSA Study Group. Cognitive changes of older adults with an equivocal amyloid load. J Neurol. 2019 Apr;266(4):835-843. doi: 10.1007/s00415-019-09203-5.