MAINTAIN - MAintain Functions and INTrinsec capacities with Aging :
Preventive and personalized INterventional Research

Equipe constitutive du CERPOP, UMR 1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
Bruno VELLAS •  chercheur


2023
  1. Aggarwal G, Morley JE, Vellas B, Nguyen AD, Butler AA; MAPT/DSA Group. Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adults. Geroscience. 2023 May 26. doi: 10.1007/s11357-023-00824-3. Epub ahead of print.
  2. Altomare D, Barkhof F, Caprioglio C, Collij LE, Scheltens P, Lopes Alves I, Bouwman F, Berkhof J, van Maurik IS, Garibotto V, Moro C, Delrieu J, Payoux P, Saint-Aubert L, Hitzel A, Molinuevo JL, Grau-Rivera O, Gispert JD, Drzezga A, Jessen F, Zeyen P, Nordberg A, Savitcheva I, Jelic V, Walker Z, Edison P, Demonet JF, Gismondi R, Farrar G, Stephens AW, Frisoni GB; Amyloid Imaging to Prevent Alzheimer’s Disease (AMYPAD) Consortium (Vellas B.collaborator). Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial. JAMA Neurol. 2023 Jun 1;80(6):548-557. doi: 10.1001/jamaneurol.2023.0997.
  3. Angioni D, Hansson O, Bateman RJ, Rabe C, Toloue M, Braunstein JB, Agus S, Sims JR, Bittner T, Carrillo MC, Fillit H, Masters CL, Salloway S, Aisen P, Weiner M, Vellas B, Gauthier S. Can We Use Blood Biomarkers as Entry Criteria and for Monitoring Drug Treatment Effects in Clinical Trials? A Report from the EU/US CTAD Task Force. J Prev Alzheimers Dis. 2023;10(3):418-425. doi: 10.14283/jpad.2023.68.
  4. Bencivenga L, Strumia M, Rolland Y, Martinez L, Cestac P, Guyonnet S, Andrieu S, Parini A, Lucas A, Vellas B, De Souto Barreto P, Rouch L; MAPT/D. S. A. group. Biomarkers of mitochondrial dysfunction and inflammaging in older adults and blood pressure variability. Geroscience. 2023 Apr;45(2):797-809. doi: 10.1007/s11357-022-00697-y.
  5. Brody M, Agronin M, Herskowitz BJ, Bookheimer SY, Small GW, Hitchinson B, Ramdas K, Wishard T, McInerney KF, Vellas B, Sierra F, Jiang Z, Mcclain-Moss L, Perez C, Fuquay A, Rodriguez S, Hare JM, Oliva AA Jr, Baumel B. Results and insights from a phase I clinical trial of Lomecel-B for Alzheimer's disease. Alzheimers Dement. 2023 Jan;19(1):261-273. doi: 10.1002/alz.12651.
  6. Caprioglio C, Ribaldi F, Visser LNC, Minguillon C, Collij LE, Grau-Rivera O, Zeyen P, Molinuevo JL, Gispert JD, Garibotto V, Moro C, Walker Z, Edison P, Demonet JF, Barkhof F, Scheltens P, Alves IL, Gismondi R, Farrar G, Stephens AW, Jessen F, Frisoni GB, Altomare D; AMYPAD consortium (Vellas B.collaborator). Analysis of Psychological Symptoms Following Disclosure of Amyloid-Positron Emission Tomography Imaging Results to Adults With Subjective Cognitive Decline. JAMA Netw Open. 2023 Jan 3;6(1):e2250921. doi: 10.1001/jamanetworkopen.2022.50921. Erratum in: JAMA Netw Open. 2023 Mar 1;6(3):e235066.
  7. de Souto Barreto P, Cesari M, Morley JE, Gonzalez-Bautista E, Rolland Y, Azzolino D, Vellas B, Fielding RA. Assessment and Management of Appetite Loss in Older Adults: An ICFSR Task Force Report. J Frailty Aging. 2023;12(1):1-6. doi: 10.14283/jfa.2022.64.
  8. Frisoni GB, Altomare D, Ribaldi F, Villain N, Brayne C, Mukadam N, Abramowicz M, Barkhof F, Berthier M, Bieler-Aeschlimann M, Blennow K, Brioschi Guevara A, Carrera E, Chételat G, Csajka C, Demonet JF, Dodich A, Garibotto V, Georges J, Hurst S, Jessen F, Kivipelto M, Llewellyn DJ, McWhirter L, Milne R, Minguillón C, Miniussi C, Molinuevo JL, Nilsson PM, Noyce A, Ranson JM, Grau-Rivera O, Schott JM, Solomon A, Stephen R, van der Flier W, van Duijn C, Vellas B, Visser LNC, Cummings JL, Scheltens P, Ritchie C, Dubois B. Dementia prevention in memory clinics: recommendations from the European task force for brain health services. Lancet Reg Health Eur. 2023 Jan 31;26:100576. doi: 10.1016/j.lanepe.2022.100576.
  9. Gagesch M, Wieczorek M, Vellas B, Kressig RW, Rizzoli R, Kanis J, Willett WC, Egli A, Lang W, Orav EJ, Bischoff-Ferrari HA. Effects of Vitamin D, Omega-3 Fatty Acids and a Home Exercise Program on Prevention of Pre-Frailty in Older Adults: The DO-HEALTH Randomized Clinical Trial. J Frailty Aging. 2023;12(1):71-77. doi: 10.14283/jfa.2022.48.
  10. Giudici KV, de Souto Barreto P, Guyonnet S, Cantet C, Zetterberg H, Boschat C, Hudry J, Andrieu S, Schmitt JAJ, Vellas B, Blennow K; NOLAN/DSA group. Effect of a 1-Year Nutritional Blend Supplementation on Plasma p-tau181 and GFAP Levels among Community-Dwelling Older Adults: A Secondary Analysis of the Nolan Trial. JAR Life. 2023 Jun 12;12:25-34. doi: 10.14283/jarlife.2023.7.
  11. Giudici KV, de Souto Barreto P, Guyonnet S, Morley JE, Nguyen AD, Aggarwal G, Parini A, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. TNFR-1 and GDF-15 Are Associated With Plasma Neurofilament Light Chain and Progranulin Among Community-Dwelling Older Adults: A Secondary Analysis of the MAPT Study. J Gerontol A Biol Sci Med Sci. 2023 Mar 30;78(4):569-578. doi: 10.1093/gerona/glac244.
  12. Gonzalez-Bautista E, de Souto Barreto P, Salinas-Rodriguez A, Manrique-Espinoza B, Sourdet S, Rolland Y, Rodríguez-Mañas L, Andrieu S, Vellas B; MAPT/DSA Group. Development and Validation of a Cutoff for the Chair Stand Test as a Screening for Mobility Impairment in the Context of the Integrated Care for Older People Program. J Gerontol A Biol Sci Med Sci. 2023 Jan 26;78(1):104-110. doi: 10.1093/gerona/glac055.
  13. Guralnik JM, Cawthon PM, Bhasin S, Fielding R, Magaziner J, Cruz-Jentoft AJ, Vellas B, Clarke L, Lattimer L, Evans W. Limited physician knowledge of sarcopenia: A survey. J Am Geriatr Soc. 2023 May;71(5):1595-1602. doi: 10.1111/jgs.18227.
  14. Hampel H, Hu Y, Cummings J, Mattke S, Iwatsubo T, Nakamura A, Vellas B, O'Bryant S, Shaw LM, Cho M, Batrla R, Vergallo A, Blennow K, Dage J, Schindler SE. Blood-based biomarkers for Alzheimer's disease: Current state and future use in a transformed global healthcare landscape. Neuron. 2023 Jun 5:S0896-6273(23)00390-2. doi: 10.1016/j.neuron.2023.05.017. Epub ahead of print.
  15. Huberty S, Freystätter G, Wieczorek M, Dawson-Hughes B, Kanis JA, Rizzoli R, Kressig RW, Vellas B, Da Silva JAP, Armbrecht G, Theiler R, Egli A, Orav EJ, Bischoff-Ferrari HA; DO-HEALTH Research Group. Association Between Multimorbidity and Rate of Falls: A 3-Year 5-Country Prospective Study in Generally Healthy and Active Community-Dwelling Adults Aged ≥70 Years. J Am Med Dir Assoc. 2023 Jun;24(6):804-810.e4. doi: 10.1016/j.jamda.2022.12.011.
  16. Lu WH, Gonzalez-Bautista E, Guyonnet S, Lucas A, Parini A, Walston JD, Vellas B, de Souto Barreto P; MAPT/DSA Group. Plasma inflammation-related biomarkers are associated with intrinsic capacity in community-dwelling older adults. J Cachexia Sarcopenia Muscle. 2023 Apr;14(2):930-939. doi: 10.1002/jcsm.13163.
  17. Mallinckrodt C, Tian Y, Aisen PS, Barkhof F, Cohen S, Dent G, Hansson O, Harrison K, Iwatsubo T, Mummery CJ, Muralidharan KK, Nestorov I, Nisenbaum L, Rajagovindan R, von Hehn C, van Dyck CH, Vellas B, Wu S, Zhu Y, Sandrock A, Chen T, Budd Haeberlein S. Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab. J Prev Alzheimers Dis. 2023;10(2):171-177. doi: 10.14283/jpad.2023.6.
  18. Middleton LT, Touchon J, Vellas B. Editorial: What Is Reasonable and Necessary for Alzheimer Patients from Randomized Clinical Trials to Clinical Practice? J Prev Alzheimers Dis. 2023;10(3):331-332. doi: 10.14283/jpad.2023.69.
  19. Perus L, Mangin JF, Deverdun J, Gutierrez LA, Gourieux E, Fischer C, Van Dokkum LEH, Manesco C, Busto G, Guyonnet S, Vellas B, Gabelle A, Le Bars E; MAPT/DSA group. Impact of multidomain preventive strategies on functional brain connectivity in older adults with cognitive complaint: Subset from the Montpellier center of the ancillary MAPT-MRI study. Front Aging Neurosci. 2023 Jan 10;14:971220. doi: 10.3389/fnagi.2022.971220.
  20. Pires Da Silva J, Wargny M, Raffin J, Croyal M, Duparc T, Combes G, Genoux A, Perret B, Vellas B, Guyonnet S, Thalamas C, Langin D, Moro C, Viguerie N, Rolland Y, Barreto PS, Cariou B, Martinez LO; MAPT/DSA Group. Plasma level of ATPase inhibitory factor 1 (IF1) is associated with type 2 diabetes risk in humans: A prospective cohort study. Diabetes Metab. 2023 Jan;49(1):101391. doi: 10.1016/j.diabet.2022.101391.
  21. Raffin J, de Souto Barreto P, Le Traon AP, Vellas B, Aubertin-Leheudre M, Rolland Y. Sedentary behavior and the biological hallmarks of aging. Ageing Res Rev. 2023 Jan;83:101807. doi: 10.1016/j.arr.2022.101807.
  22. Raffin J, Rolland Y, Fischer C, Mangin JF, Gabelle A, Vellas B, de Souto Barreto P; MAPT/DSA Group. Cross-sectional associations between cortical thickness and physical activity in older adults with spontaneous memory complaints: The MAPT Study. J Sport Health Sci. 2023 May;12(3):324-332. doi: 10.1016/j.jshs.2021.01.011.
  23. Raffin J, Rolland Y, Parini A, Lucas A, Guyonnet S, Vellas B, de Souto Barreto P; MAPT/DSA Group. Association between physical activity, growth differentiation factor 15 and bodyweight in older adults: A longitudinal mediation analysis. J Cachexia Sarcopenia Muscle. 2023 Jan 20;14(2):771–80. doi: 10.1002/jcsm.13152. Epub ahead of print.
  24. Rolland Y, Dray C, Vellas B, Barreto PS. Current and investigational medications for the treatment of sarcopenia. Metabolism. 2023 Jun 20:155597. doi: 10.1016/j.metabol.2023.155597. Epub ahead of print.
  25. Sánchez-Sánchez JL, Ader I, Jeanson Y, Planat-Benard V, Vellas B, Casteilla L, de Souto-Barreto P. Periostin Plasma Levels and Changes on Physical and Cognitive Capacities in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2023 Mar 1;78(3):424-432. doi: 10.1093/gerona/glac226.
  26. Silva JAD, Martinez LO, Rolland Y, Najib S, Croyal M, Perret B, Jabrane-Ferrat N, El Costa H, Guyonnet S, Vellas B, Barreto PS; MAPT/DSA group. Plasma Level of ATPase Inhibitory Factor 1 (IF1) and intrinsic capacity in community-dwelling older adults: Prospective data from the MAPT Study. J Gerontol A Biol Sci Med Sci. 2023 Jun 6:glad142. doi: 10.1093/gerona/glad142. Epub ahead of print.
  27. Stuck AK, Tsai LT, Freystaetter G, Vellas B, Kanis JA, Rizzoli R, Kressig KS, Armbrecht G, Da Silva JAP, Dawson-Hughes B, Egli A, Bischoff-Ferrari HA. Comparing Prevalence of Sarcopenia Using Twelve Sarcopenia Definitions in a Large Multinational European Population of Community-Dwelling Older Adults. J Nutr Health Aging. 2023;27(3):205-212. doi: 10.1007/s12603-023-1888-y.
  28. Stuck AK, Tsai LT, Freystaetter G, Vellas B, Kanis JA, Rizzoli R, Kressig KS, Armbrecht G, Da Silva JAP, Dawson-Hughes B, Egli A, Bischoff-Ferrari HA. Comparing Prevalence of Sarcopenia Using Twelve Sarcopenia Definitions in a Large Multinational European Population of Community-Dwelling Older Adults. J Nutr Health Aging. 2023;27(3):205-212. doi: 10.1007/s12603-023-1888-y.
  29. van Dyck CH, Swanson CJ, Aisen P, Bateman RJ, Chen C, Gee M, Kanekiyo M, Li D, Reyderman L, Cohen S, Froelich L, Katayama S, Sabbagh M, Vellas B, Watson D, Dhadda S, Irizarry M, Kramer LD, Iwatsubo T. Lecanemab in Early Alzheimer's Disease. N Engl J Med. 2023 Jan 5;388(1):9-21. doi: 10.1056/NEJMoa2212948.
  30. Vellas B. How to Implement Integrated Care for Older Persons-ICOPE-Massively in Clinical Practice for a Healthy Longevity. JAR Life. 2023 May 24;12:18-19. doi: 10.14283/jarlife.2023.4.
  31. Vlietstra L, Kirk B, Duque G, Qualls C, Vellas B, Andrieu S, Morley JE, Waters DL. Using minimal clinically important differences to measure long-term transitions of osteosarcopenia: The New Mexico Aging Process Study. Exp Gerontol. 2023 Mar;173:112106. doi: 10.1016/j.exger.2023.112106.

Bruno VELLAS • Publications 2022 • Publications 2021 I Publications 2020 I Publications 2019